Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 12/20 | 0.52 |
| ▸ | NHERF1 | O14745 | 3/20 | 0.47 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | GOT1 | P17174 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30885446 | 0.94 | STING1 (0.50) | STING1NHERF1SNCACNR1GOT1 | |
| SCHEMBL30885392 | 0.93 | STING1 (0.49) | STING1NHERF1SNCACNR1GOT1 | |
| SCHEMBL30885409 | 0.92 | STING1 (0.48) | STING1NHERF1SNCACNR1GOT1 | |
| SCHEMBL30885461 | 0.90 | NHERF1 (0.51) | STING1NHERF1SNCANTRK1 | |
| SCHEMBL30885375 | 0.90 | STING1 (0.54) | STING1NHERF1SNCAGOT1 | |
| SCHEMBL30885433 | 0.89 | STING1 (0.53) | STING1 | |
| SCHEMBL30885402 | 0.86 | NHERF1 (0.48) | STING1NHERF1SNCANTRK1 | |
| SCHEMBL30885423 | 0.83 | STING1 (0.51) | STING1 | |
| SCHEMBL30885459 | 0.83 | STING1 (0.51) | STING1NHERF1SNCA | |
| SCHEMBL30885432 | 0.83 | NHERF1 (0.52) | STING1NHERF1SNCANTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117756698-A | Urea compound and medical application thereof as STING inhibitor | 中国药科大学 | 2024-03-26 | — | — | CN | disclosed |