Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 1/20 | 0.34 |
| ▸ | CLK1 | P49759 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 3/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 2/20 | 0.30 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.30 |
| ▸ | GLRB | P48167 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31254514 | 1.00 | METTL3 (0.34) | METTL3CLK1DYRK1ADYRK1BRIPK2 | |
| SCHEMBL30886369 | 0.84 | PRMT5 (0.31) | RIPK2PRMT5WDR77ALDH1A1DRD2 | |
| SCHEMBL25324534 | 0.80 | ALDH1A1 (0.34) | CLK1DYRK1ADYRK1BRIPK2PRMT5 | |
| SCHEMBL25324531 | 0.80 | ALDH1A1 (0.34) | CLK1DYRK1ADYRK1BRIPK2PRMT5 | |
| SCHEMBL25327271 | 0.80 | ALDH1A1 (0.34) | CLK1DYRK1ADYRK1BRIPK2PRMT5 | |
| SCHEMBL30522987 | 0.80 | ALDH1A1 (0.34) | CLK1DYRK1ADYRK1BRIPK2PRMT5 | |
| SCHEMBL25913598 | 0.80 | ALDH1A1 (0.34) | CLK1DYRK1ADYRK1BRIPK2PRMT5 | |
| SCHEMBL25320666 | 0.79 | PRMT5 (0.39) | CLK1DYRK1ADYRK1BRIPK2PRMT5 | |
| SCHEMBL30470212 | 0.79 | PRMT5 (0.39) | CLK1DYRK1ADYRK1BRIPK2PRMT5 | |
| SCHEMBL24365117 | 0.79 | PRMT5 (0.39) | CLK1DYRK1ADYRK1BRIPK2PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118047793-A | Pyridine derivative and application thereof | 成都百裕制药股份有限公司 | 2024-05-17 | — | — | CN | disclosed |