Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | CD38 | P28907 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ASPH | Q12797 | 1/20 | 0.44 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.44 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29410010 | 0.81 | MAPT (0.58) | GAAPOLBMAPTSMN1; SMN2KMT2A | |
| SCHEMBL22712548 | 0.81 | MAPT (0.58) | GAAPOLBMAPTSMN1; SMN2KMT2A | |
| SCHEMBL22712456 | 0.81 | MAPT (0.58) | GAAPOLBMAPTSMN1; SMN2KMT2A | |
| SCHEMBL31252847 | 0.80 | GAA (0.56) | GAAMAPTCD38SMN1; SMN2KMT2A | |
| SCHEMBL15270392 | 0.80 | GAA (0.56) | GAAMAPTCD38SMN1; SMN2KMT2A | |
| SCHEMBL25151518 | 0.79 | GAA (0.53) | GAAPOLBMAPTKMT2AKDM4E | |
| SCHEMBL30593191 | 0.79 | GAA (0.53) | GAAPOLBMAPTKMT2AKDM4E | |
| SCHEMBL31361060 | 0.78 | CD38 (0.52) | GAACD38KMT2AKDM4EMEN1 | |
| SCHEMBL31522867 | 0.77 | MAPT (0.53) | GAAPOLBMAPTSMN1; SMN2TP53 | |
| SCHEMBL23015337 | 0.75 | KDM4E (0.48) | POLBMAPTCD38KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119855815-A | KRAS mutant protein inhibitor, and preparation method and application thereof | 甘李药业股份有限公司 | 2025-04-18 | — | — | CN | disclosed |
| WO-2024061333-A1 | KRAS MUTANT PROTEIN INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | 甘李药业股份有限公司 | 2024-03-28 | — | — | WO | disclosed |