Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD38 | P28907 | 1/20 | 0.52 |
| ▸ | NCF1 | P14598 | 1/20 | 0.47 |
| ▸ | VNN1 | O95497 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ASPH | Q12797 | 1/20 | 0.46 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.46 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 2/20 | 0.45 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.45 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.45 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | ACP1 | P24666 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27033267 | 0.84 | KDM4C (0.51) | KDM4ERPS6KB1MEN1KMT2AGAA | |
| SCHEMBL30595530 | 0.84 | KDM4C (0.51) | KDM4ERPS6KB1MEN1KMT2AGAA | |
| SCHEMBL2481240 | 0.80 | KDM4E (0.56) | CD38VNN1KDM4EASPHRIOX2 | |
| SCHEMBL30887705 | 0.78 | GAA (0.52) | CD38KDM4EASPHRIOX2KDM8 | |
| SCHEMBL23039888 | 0.78 | CD38 (0.51) | CD38NCF1VNN1KDM4EASPH | |
| SCHEMBL29499779 | 0.78 | CD38 (0.51) | CD38NCF1VNN1KDM4EASPH | |
| SCHEMBL18755669 | 0.77 | MEN1 (0.46) | NCF1KDM4EASPHRIOX2KDM8 | |
| SCHEMBL20061544 | 0.75 | AURKA (0.59) | VNN1AURKARPS6KB1MEN1KMT2A | |
| SCHEMBL9262572 | 0.75 | KDM4E (0.60) | CD38VNN1KDM4EAURKARPS6KB1 | |
| SCHEMBL29692343 | 0.74 | PDE5A (0.50) | NCF1KDM4EASPHRIOX2KDM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119176820-A | Tricyclic compounds as MAT2A inhibitors | 艾立康药业股份有限公司 | 2024-12-24 | — | — | CN | disclosed |