Sugi Predict

Sugi Predict / Compounds / SCHEMBL30888269

SCHEMBL30888269

SCHEMBL30888269

CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CC(=O)O)C(C)C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.73

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ NPY2R P49146 8/20 0.70
▸ NPY4R P50391 8/20 0.70
▸ NPY5R Q15761 8/20 0.70
▸ NPY1R P25929 6/20 0.70
▸ EP300 Q09472 1/20 0.64
▸ HIF1A Q16665 1/20 0.64
▸ TFPI P10646 4/20 0.62
▸ KDM1A O60341 2/20 0.60
▸ MAOB P27338 1/20 0.60
▸ KDM5A P29375 1/20 0.60
▸ KDM1B Q8NB78 1/20 0.60
▸ CALCR P30988 3/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29521469 0.92 NPY2R (0.61) NPY2RNPY4RNPY5RNPY1R
SCHEMBL30712967 0.90 NPY2R (0.69) NPY2RNPY4RNPY5RNPY1REP300
SCHEMBL30567738 0.90 NPY2R (0.68) NPY2RNPY4RNPY5RNPY1REP300
SCHEMBL31020752 0.90 NPY2R (0.64) NPY2RNPY4RNPY5RNPY1REP300
SCHEMBL29805442 0.90 NPY2R (0.63) NPY2RNPY4RNPY5RNPY1REP300
SCHEMBL30607379 0.90 NPY2R (0.69) NPY2RNPY4RNPY5RNPY1REP300
Savcipsgqpcpyskyccsgsctyktnengnsvqrcd SCHEMBL29838758 0.89 NPY2R (0.69) NPY2RNPY4RNPY5RNPY1REP300
Sstcipsgqpcpynenccsqsctykenengntvkrcd SCHEMBL29838759 0.89 NPY2R (0.67) NPY2RNPY4RNPY5RNPY1REP300
SCHEMBL30581208 0.89 NPY2R (0.59) NPY2RNPY4RNPY5RNPY1REP300
SCHEMBL30262093 0.88 NPY2R (0.61) NPY2RNPY4RNPY5RNPY1REP300

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240101634-A1 hAM15-52 ANALOGUES WITH IMPROVED AMYLIN RECEPTOR (hAMY3R) POTENCY Gubra A/S (DK) 2024-03-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240101634-A1 hAM15-52 ANALOGUES WITH IMPROVED AMYLIN RECEPTOR (hAMY3R) POTENCY GLP1R, GIPR, GPR119 NPY2R 75/4885NPY4R 79/4885NPY5R 92/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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