SCHEMBL29521469

CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	NPY2R	P49146	7/20	0.61

▸	NPY4R	P50391	7/20	0.61

▸	NPY5R	Q15761	7/20	0.61

▸	NPY1R	P25929	5/20	0.61

▸	OPRD1	P41143	2/20	0.59

▸	NMUR2	Q9GZQ4	3/20	0.59

▸	NMUR1	Q9HB89	3/20	0.59

▸	C5AR1	P21730	1/20	0.59

▸	NTSR1	P30989	4/20	0.59

▸	NTSR2	O95665	2/20	0.58

▸	SORT1	Q99523	2/20	0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30001568	0.93	RAMP3 (0.60)	NPY2RNPY4RNPY5RNPY1ROPRD1
SCHEMBL30888269	0.92	NPY2R (0.70)	NPY2RNPY4RNPY5RNPY1R
SCHEMBL31020752	0.89	NPY2R (0.64)	NPY2RNPY4RNPY5RNPY1RNMUR2
SCHEMBL30262198	0.89	EP300 (0.64)	NPY2RNPY4RNPY5RNPY1RNMUR2
SCHEMBL30607429	0.88	NPY2R (0.66)	NPY2RNPY4RNPY5RNPY1ROPRD1
SCHEMBL31129141	0.88	C5AR1 (0.59)	NPY2RNPY4RNPY5RNPY1ROPRD1
SCHEMBL29993834	0.88	NTSR1 (0.66)	NTSR1NTSR2SORT1
SCHEMBL31519870	0.88	OPRD1 (0.66)	OPRD1NTSR1NTSR2SORT1
SCHEMBL29649229	0.88	NPY2R (0.67)	NPY2RNPY4RNPY5RNPY1R
SCHEMBL30262093	0.88	NPY2R (0.61)	NPY2RNPY4RNPY5RNPY1ROPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-4021929-A1	HAM15-52 ANALOGUES WITH IMPROVED AMYLIN RECEPTOR (HAMY3R) POTENCY	Gubra ApS (DK)	2022-07-06	—	—	EP	disclosed
WO-2022063925-A1	HAM15-52 ANALOGUES WITH IMPROVED AMYLIN RECEPTOR (HAMY3R) POTENCY	GUBRA APS (DK)	2022-03-31	—	—	WO	disclosed