Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 20/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 14/20 | 0.39 |
| ▸ | KIT | P10721 | 4/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 7/20 | 0.39 |
| ▸ | FLT3 | P36888 | 4/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21425505 | 1.00 | CSF1R (0.39) | CSF1RPDGFRAKITPDGFRBFLT3 | |
| SCHEMBL21425525 | 0.83 | CSF1R (0.41) | CSF1RPDGFRAKITPDGFRBFLT3 | |
| SCHEMBL21426331 | 0.81 | MTOR (0.41) | CSF1RPDGFRAKITPDGFRBFLT3 | |
| SCHEMBL21426311 | 0.80 | CSF1R (0.59) | CSF1RPDGFRAKITPDGFRBFLT3 | |
| SCHEMBL30086983 | 0.80 | CSF1R (0.59) | CSF1RPDGFRAKITPDGFRBFLT3 | |
| SCHEMBL21426310 | 0.76 | PIN1 (0.37) | — | |
| SCHEMBL27155120 | 0.75 | ALDH1A1 (0.33) | CSF1R | |
| SCHEMBL16028609 | 0.74 | CSF1R (0.52) | CSF1RPDGFRAKITPDGFRBFLT3 | |
| SCHEMBL21771999 | 0.73 | CSF1R (0.75) | CSF1RPDGFRAKITPDGFRB | |
| SCHEMBL21786232 | 0.72 | MET (0.39) | CYP2C9KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3632907-B1 | N-(AZAARYL)CYCLOLACTAM-1-CARBOXAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | ABBISKO THERAPEUTICS CO LTD (CN) | 2024-02-28 | — | — | EP | disclosed |