Sugi Predict

Sugi Predict / Compounds / SCHEMBL3089094

SCHEMBL3089094

SCHEMBL3089094

[c]1c(-c2ccc3ccccc3c2)cccc1-c1ccc2ccccc2c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HSD17B1 P14061 1/20 0.50
▸ HSD17B2 P37059 1/20 0.50
▸ GSTP1 P09211 1/20 0.48
▸ ESR1 P03372 1/20 0.48
▸ ESR2 Q92731 1/20 0.48
▸ ALOX5 P09917 1/20 0.47
▸ CYP1A2 P05177 4/20 0.42
▸ CYP11B1 P15538 3/20 0.42
▸ CYP11B2 P19099 3/20 0.42
▸ CYP17A1 P05093 1/20 0.42
▸ CYP19A1 P11511 1/20 0.42
▸ CA1 P00915 2/20 0.41
▸ CA2 P00918 2/20 0.41
▸ SMN1; SMN2 Q16637 2/20 0.41
▸ CA9 Q16790 1/20 0.41
▸ ALDH1A1 P00352 3/20 0.40
▸ CYP2C9 P11712 1/20 0.40
▸ HPGD P15428 1/20 0.40
▸ CYP2C19 P33261 1/20 0.40
▸ NPSR1 Q6W5P4 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29104462 0.88 HSD17B1 (0.44) HSD17B1HSD17B2GSTP1ESR1ESR2
SCHEMBL1719526 0.81 GSTP1 (0.44) HSD17B1HSD17B2GSTP1ESR1ESR2
SCHEMBL291173 0.79 GSTP1 (0.42) HSD17B1HSD17B2GSTP1ESR1ESR2
SCHEMBL948858 0.78 GSTP1 (0.45) HSD17B1HSD17B2GSTP1ESR1ESR2
SCHEMBL30603836 0.77 ESR1 (0.71) HSD17B1HSD17B2GSTP1ESR1ESR2
SCHEMBL30239993 0.77 ESR1 (0.71) HSD17B1HSD17B2GSTP1ESR1ESR2
SCHEMBL15902840 0.77 ESR1 (0.71) HSD17B1HSD17B2GSTP1ESR1ESR2
SCHEMBL30239998 0.77 ESR1 (0.71) HSD17B1HSD17B2GSTP1ESR1ESR2
SCHEMBL239121 0.77 ESR1 (0.71) HSD17B1HSD17B2GSTP1ESR1ESR2
SCHEMBL5013872 0.77 ESR1 (0.71) HSD17B1HSD17B2GSTP1ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10381579-B2 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-08-13 — — US claimed
US-20150249225-A1 STABILITY OLED MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-09-03 — — US claimed
US-9051344-B2 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2015-06-09 — — US claimed
EP-1878053-B1 STABILITY OLED MATERIALS AND DEVICES WITH IMPROVED STABILITY UNIVERSAL DISPLAY CORP (US) 2009-08-26 — — EP claimed
US-11404650-B2 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-08-02 — — US disclosed
US-10381579-B2 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-08-13 — — US disclosed
EP-2251316-B1 METHOD FOR PRODUCING OPTICALLY ACTIVE ESTER AND METHOD FOR PRODUCING OPTICALLY ACTIVE CARBOXYLIC ACID TOKYO UNIV OF SCIENCE EDUCATIONAL FOUNDATION ADMINISTRATIVE ORGANIZATION (JP) 2018-02-21 — — EP disclosed
CN-107011388-A Stability OLED materials and the device with improved stability 通用显示公司 2017-08-04 — — CN disclosed
US-20150249225-A1 STABILITY OLED MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-09-03 — — US disclosed
CN-101180304-B Stable OLED materials and devices with improved stability UNIVERSAL DISPLAY CORP. (US) 2015-08-19 — — CN disclosed
US-9051344-B2 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2015-06-09 — — US disclosed
US-7902374-B2 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2011-03-08 — — US disclosed
EP-2251316-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE ESTER AND METHOD FOR PRODUCING OPTICALLY ACTIVE CARBOXYLIC ACID Tokyo University Of Science Educational Foundation Administrative Organization (JP) 2010-11-17 — — EP disclosed
US-20100234610-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE ESTER AND METHOD FOR PRODUCING OPTICALLY ACTIVE CARBOXYLIC ACID TOKYO UNIVERSITY OF SCIENCE EDUCATIONAL FOUNDATION ADMINISTRATIVE ORGANIZATION (JP) 2010-09-16 — — US disclosed
EP-1878053-B1 STABILITY OLED MATERIALS AND DEVICES WITH IMPROVED STABILITY UNIVERSAL DISPLAY CORP (US) 2009-08-26 — — EP disclosed
WO-2008054584-A1 IMPROVED STABILITY OLED MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2008-05-08 — — WO disclosed
EP-1878053-A1 STABILITY OLED MATERIALS AND DEVICES WITH IMPROVED STABILITY Universal Display Corporation (US) 2008-01-16 — — EP disclosed
US-20070088167-A1 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION 2007-04-19 — — US disclosed
WO-2006121811-A1 STABILITY OLED MATERIALS AND DEVICES WITH IMPROVED STABILITY UNIVERSAL DISPLAY CORPORATION (US) 2006-11-16 — — WO disclosed
US-20060251923-A1 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION 2006-11-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11404650-B2 Stability OLED materials and devices OCIAD2, OCIAD1, OSBP2 HSD17B1 2223/4885HSD17B2 1951/4885GSTP1 1572/4885
US-10381579-B2 Stability OLED materials and devices OCIAD2, OCIAD1, OSBP2 HSD17B1 2168/4885HSD17B2 1907/4885GSTP1 1548/4885
US-20100234610-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE ESTER AND METHOD FOR PRODUCING OPTICALLY ACTIVE CARBOXYLIC ACID ACADM, ADH5, ALDH7A1 HSD17B1 447/4885HSD17B2 909/4885GSTP1 3152/4885
US-20150249225-A1 STABILITY OLED MATERIALS AND DEVICES OCIAD2, OCIAD1, OSBP2 HSD17B1 2168/4885HSD17B2 1907/4885GSTP1 1548/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.