Sugi Predict

Sugi Predict / Compounds / SCHEMBL30891306

SCHEMBL30891306

SCHEMBL30891306

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nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ MMP13 P45452 1/20 0.47
▸ FGF1 P05230 2/20 0.41
▸ FGF2 P09038 2/20 0.41
▸ VEGFA P15692 2/20 0.41
▸ HPSE Q9Y251 2/20 0.41
▸ CD209 Q9NNX6 2/20 0.40
▸ SLC6A2 P23975 2/20 0.39
▸ PRKCA P17252 1/20 0.39
▸ LGALS8 O00214 1/20 0.39
▸ TACR1 P25103 1/20 0.37
▸ SIRT2 Q8IXJ6 1/20 0.37
▸ MDK P21741 1/20 0.36
▸ LGALS3 P17931 1/20 0.36
▸ MAOB P27338 1/20 0.36
▸ HTT P42858 1/20 0.35
▸ GJB2 P29033 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30891378 0.96 MMP13 (0.46) MMP13FGF1FGF2VEGFAHPSE
SCHEMBL29880337 0.96 MMP13 (0.46) MMP13FGF1FGF2VEGFAHPSE
SCHEMBL30891312 0.96 MMP13 (0.46) MMP13FGF1FGF2VEGFAHPSE
SCHEMBL30891369 0.96 MMP13 (0.46) MMP13FGF1FGF2VEGFAHPSE
SCHEMBL15130853 0.94 MMP13 (0.47) MMP13FGF1FGF2VEGFAHPSE
SCHEMBL30891501 0.93 MMP13 (0.42) MMP13FGF1FGF2VEGFAHPSE
SCHEMBL30891307 0.93 MMP13 (0.46) MMP13FGF1FGF2VEGFAHPSE
SCHEMBL30391583 0.93 MMP13 (0.46) MMP13FGF1FGF2VEGFAHPSE
SCHEMBL30891273 0.93 MMP13 (0.46) MMP13FGF1FGF2VEGFAHPSE
SCHEMBL30891488 0.92 MMP13 (0.45) MMP13FGF1FGF2VEGFAHPSE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260021190-A1 GLUCOSE-RESPONSIVE INSULIN CONJUGATES COMPRISING A PENTA-VALENT SUGAR CLUSTER FOR TREATMENT OF DIABETES MERCK SHARP & DOHME LLC (US) 2026-01-22 — — US disclosed
EP-4615487-A1 GLUCOSE-RESPONSIVE INSULIN CONJUGATES COMPRISING A PENTA-VALENT SUGAR CLUSTER FOR TREATMENT OF DIABETES Merck Sharp & Dohme LLC (US) 2025-09-17 — — EP disclosed
WO-2024102633-A1 GLUCOSE-RESPONSIVE INSULIN CONJUGATES COMPRISING A PENTA-VALENT SUGAR CLUSTER FOR TREATMENT OF DIABETES MERCK SHARP & DOHME LLC (US) 2024-05-16 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260021190-A1 GLUCOSE-RESPONSIVE INSULIN CONJUGATES COMPRISING A PENTA-VALENT SUGAR CLUSTER FOR TREATMENT OF DIABETES INSR, GPR119, GLP1R MMP13 1271/4885FGF1 1543/4885FGF2 2234/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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