Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.42 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HCAR1 | Q9BXC0 | 8/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30891705 | 0.98 | MAPKAPK2 (0.41) | MAPKAPK2RPS6KA3CSNK2A1PLK3PDE3B | |
| SCHEMBL4056355 | 0.78 | PDE3B (0.43) | PDE3BPDE3ACA12CA1CA3 | |
| SCHEMBL24885835 | 0.78 | TYRO3 (0.49) | PDE3BPDE3ACA12CA1CA3 | |
| SCHEMBL20660448 | 0.74 | HCAR1 (0.41) | PDE3BPDE3AALDH1A1CA12CA1 | |
| SCHEMBL1983844 | 0.72 | ALDH1A1 (0.43) | MAPKAPK2RPS6KA3CSNK2A1PLK3PDE3B | |
| SCHEMBL17376499 | 0.71 | ALDH1A1 (0.42) | MAPKAPK2RPS6KA3CSNK2A1PLK3ALDH1A1 | |
| SCHEMBL17165045 | 0.71 | ALDH1A1 (0.47) | MAPKAPK2ALDH1A1MAPK1RXFP1 | |
| SCHEMBL30827053 | 0.71 | ALDH1A1 (0.47) | MAPKAPK2ALDH1A1MAPK1RXFP1 | |
| SCHEMBL22497903 | 0.69 | PDE3B (0.44) | MAPKAPK2RPS6KA3CSNK2A1PLK3PDE3B | |
| SCHEMBL30891689 | 0.69 | PDE3B (0.44) | MAPKAPK2RPS6KA3CSNK2A1PLK3PDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117777123-A | Pyrimidine bicyclo compounds and application thereof | 江苏开元药业有限公司 | 2024-03-29 | — | — | CN | disclosed |