Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | GPR3 | P46089 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | TNKS | O95271 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.57 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.57 |
| ▸ | DAO | P14920 | 1/20 | 0.53 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.51 |
| ▸ | CDC25A | P30304 | 1/20 | 0.51 |
| ▸ | CDC25C | P30307 | 1/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.50 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22866497 | 1.00 | PARP1 (0.57) | PARP1ALDH1A1KDM4EGPR3HSD17B10 | |
| SCHEMBL27968034 | 0.85 | PARP1 (0.58) | PARP1ALDH1A1KDM4EGPR3HSD17B10 | |
| SCHEMBL30466767 | 0.85 | PARP1 (0.57) | PARP1ALDH1A1KDM4EGPR3HSD17B10 | |
| SCHEMBL20227584 | 0.85 | PARP1 (0.57) | PARP1ALDH1A1KDM4EGPR3HSD17B10 | |
| SCHEMBL25835543 | 0.83 | CDC25A (0.56) | PARP1ALDH1A1KDM4EMEN1LMNA | |
| SCHEMBL13802973 | 0.78 | PARP1 (0.57) | PARP1ALDH1A1KDM4EGPR3HSD17B10 | |
| SCHEMBL31714622 | 0.78 | ALDH1A1 (0.61) | PARP1ALDH1A1KDM4EGPR3HSD17B10 | |
| SCHEMBL9709372 | 0.78 | ALDH1A1 (0.61) | PARP1ALDH1A1KDM4EGPR3HSD17B10 | |
| SCHEMBL1613016 | 0.78 | PARP1 (0.57) | PARP1ALDH1A1KDM4EGPR3HSD17B10 | |
| SCHEMBL6009673 | 0.76 | GABRP (0.61) | PARP1ALDH1A1KDM4EGPR3HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269756-B | 4-Oxo-3, 4-dihydropyrido [3,4-D ] pyrimidine compounds that inhibit EIF4E | 效应疗法股份有限公司 | 2024-05-14 | — | — | CN | disclosed |