Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | FNTA | P49354 | 2/20 | 0.44 |
| ▸ | FNTB | P49356 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MDH2 | P40926 | 1/20 | 0.43 |
| ▸ | NQO1 | P15559 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6669751 | 0.75 | KDM4E (0.68) | MAPTALDH1A1FNTAFNTBSMN1; SMN2 | |
| SCHEMBL2087913 | 0.75 | TSHR (0.55) | MAPTALDH1A1NPSR1HTTHPGD | |
| SCHEMBL11488750 | 0.74 | TBXAS1 (0.64) | FNTAFNTBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6669255 | 0.74 | EGFR (0.56) | MAPTALDH1A1FNTAFNTBHTT | |
| SCHEMBL14074159 | 0.73 | MAPT (0.57) | MAPTALDH1A1NPSR1HTTTSHR | |
| SCHEMBL11494180 | 0.71 | HTR2A (0.67) | MAPTFNTAFNTB | |
| SCHEMBL12451681 | 0.70 | HTT (0.54) | MAPTALDH1A1HTTHPGDMDH2 | |
| SCHEMBL8665875 | 0.70 | MAPT (0.51) | MAPTALDH1A1NPSR1NPC1RAB9A | |
| SCHEMBL28118179 | 0.70 | MAPT (0.43) | MAPTALDH1A1NPSR1HTTHPGD | |
| SCHEMBL7894073 | 0.69 | TSHR (0.59) | MAPTHPGDTSHRSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201896-A | PI 3K-alpha inhibitors and methods of use thereof | 传达治疗有限公司 | 2024-06-14 | — | — | CN | disclosed |