Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 9/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 9/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 9/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 9/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 9/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 9/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.41 |
| ▸ | PSMB8 | P28062 | 3/20 | 0.41 |
| ▸ | PSMB9 | P28065 | 3/20 | 0.41 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.41 |
| ▸ | PSMB10 | P40306 | 2/20 | 0.41 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 3/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | REN | P00797 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30930720 | 0.96 | ACE (0.42) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL31501260 | 0.96 | ABCB1 (0.41) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL31247975 | 0.95 | ABCB1 (0.41) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL31247896 | 0.94 | PSEN1 (0.40) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL31247969 | 0.92 | ABCB1 (0.40) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL31247966 | 0.92 | OPRM1 (0.40) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL31296842 | 0.92 | CCKBR (0.41) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL31247960 | 0.92 | OPRD1 (0.40) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL31247874 | 0.91 | PTPN1 (0.46) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL38652065 | 0.90 | PSEN1 (0.43) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118005767-A | Method for preparing Tirzepatide by combining solid and liquid | 柏佳薇(深圳)生物科技有限公司 | 2024-05-10 | — | — | CN | claimed |
| CN-118005767-A | Method for preparing Tirzepatide by combining solid and liquid | 柏佳薇(深圳)生物科技有限公司 | 2024-05-10 | — | — | CN | disclosed |