Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30268850 | 0.90 | CNR2 (0.46) | NOTUMTBXAS1CYP1A2KDM4EALDH1A1 | |
| SCHEMBL24036185 | 0.90 | NOTUM (0.48) | NOTUMTBXAS1CYP1A2KDM4EALDH1A1 | |
| SCHEMBL28934829 | 0.85 | NOTUM (0.49) | NOTUMTBXAS1CYP1A2KDM4EALDH1A1 | |
| SCHEMBL24842023 | 0.84 | MEN1 (0.40) | CNR2POLBCYP4F2CYP4A11MEN1 | |
| SCHEMBL24842800 | 0.84 | MEN1 (0.40) | CNR2POLBCYP4F2CYP4A11MEN1 | |
| SCHEMBL29065096 | 0.82 | NOTUM (0.47) | NOTUMTBXAS1CYP1A2KDM4EALDH1A1 | |
| SCHEMBL20857112 | 0.82 | NOTUM (0.47) | NOTUMTBXAS1CYP1A2KDM4EALDH1A1 | |
| SCHEMBL25153647 | 0.82 | NOTUM (0.51) | NOTUMCYP1A2KDM4EALDH1A1HPGD | |
| SCHEMBL26813648 | 0.81 | CPB2 (0.42) | POLBCYP4F2CYP4A11MEN1KMT2A | |
| SCHEMBL22859643 | 0.80 | NOTUM (0.45) | NOTUMTBXAS1CYP1A2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024097948-A1 | DEGRADERS OF MDM2 AND USES THEREOF | ROIVANT DISCOVERY, INC. (US) | 2024-05-10 | — | — | WO | disclosed |