Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | MMP1 | P03956 | 6/20 | 0.48 |
| ▸ | MMP2 | P08253 | 6/20 | 0.48 |
| ▸ | MMP9 | P14780 | 6/20 | 0.48 |
| ▸ | MAOA | P21397 | 4/20 | 0.48 |
| ▸ | MAOB | P27338 | 4/20 | 0.48 |
| ▸ | EGFR | P00533 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALPG | P10696 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.45 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.45 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.43 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30894581 | 0.91 | RXRA (0.65) | RXRAMAPTMMP1MMP2MMP9 | |
| SCHEMBL30894580 | 0.85 | RXRA (0.54) | RXRAMAPTMMP1MMP2MMP9 | |
| SCHEMBL30894574 | 0.84 | RXRA (0.61) | RXRAMAPTMMP1MMP2MMP9 | |
| SCHEMBL30894568 | 0.82 | RXRA (0.66) | RXRAMAPTMMP1MMP2MMP9 | |
| SCHEMBL30894579 | 0.81 | RXRA (0.80) | RXRAMAPTEGFRNPC1RAB9A | |
| SCHEMBL30894582 | 0.80 | RXRA (0.55) | RXRAMAPTMMP1MMP2MMP9 | |
| SCHEMBL30894571 | 0.75 | RXRA (0.72) | RXRAMAPTMAOBEGFRNPC1 | |
| SCHEMBL30894572 | 0.75 | RXRA (0.66) | RXRAMAPTMMP1MMP2MMP9 | |
| SCHEMBL30894577 | 0.75 | CDK1 (0.50) | RXRAMAPTMMP1MMP2MMP9 | |
| SCHEMBL30366881 | 0.75 | RXRA (0.85) | RXRANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117645568-A | N- ([ 4,4' -bipyridine ] -2-yl) cinnamamide derivative, and preparation and application thereof | 厦门大学 | 2024-03-05 | — | — | CN | disclosed |