Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | MMP1 | P03956 | 5/20 | 0.45 |
| ▸ | MMP2 | P08253 | 5/20 | 0.45 |
| ▸ | MMP9 | P14780 | 5/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30894568 | 0.90 | RXRA (0.66) | RXRAMAPTMMP1MMP2MMP9 | |
| SCHEMBL30894577 | 0.90 | CDK1 (0.50) | RXRAMAPTMMP1MMP2MMP9 | |
| SCHEMBL30894574 | 0.87 | RXRA (0.61) | RXRAMAPTMMP1MMP2MMP9 | |
| SCHEMBL30894589 | 0.85 | RXRA (0.64) | RXRAMAPTMMP1MMP2MMP9 | |
| SCHEMBL30894572 | 0.83 | RXRA (0.66) | RXRAMAPTMMP1MMP2MMP9 | |
| SCHEMBL30894582 | 0.82 | RXRA (0.55) | RXRAMAPTMMP1MMP2MMP9 | |
| SCHEMBL30366946 | 0.81 | RXRA (0.82) | RXRAMAPTMMP1MMP2MMP9 | |
| SCHEMBL30894584 | 0.78 | RXRA (0.59) | RXRAMAPTALDH1A1 | |
| SCHEMBL30894581 | 0.77 | RXRA (0.65) | RXRAMAPTMMP1MMP2MMP9 | |
| SCHEMBL30894565 | 0.72 | MMP1 (0.47) | MAPTMMP1MMP2MMP9EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117645568-A | N- ([ 4,4' -bipyridine ] -2-yl) cinnamamide derivative, and preparation and application thereof | 厦门大学 | 2024-03-05 | — | — | CN | disclosed |