Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | KARS1 | Q15046 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | RELA | Q04206 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30894572 | 0.93 | RXRA (0.66) | RXRAMAPTKARS1NPC1RAB9A | |
| SCHEMBL30366946 | 0.90 | RXRA (0.82) | RXRAMAPTKARS1NPC1RAB9A | |
| SCHEMBL30894580 | 0.90 | RXRA (0.54) | RXRAMAPTKARS1ALDH1A1MMP1 | |
| SCHEMBL30894584 | 0.88 | RXRA (0.59) | RXRAMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30894589 | 0.82 | RXRA (0.64) | RXRAMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30894579 | 0.82 | RXRA (0.80) | RXRAMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30894577 | 0.79 | CDK1 (0.50) | RXRAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL30367547 | 0.79 | RXRA (0.82) | RXRANPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL30576121 | 0.77 | MAPK14 (0.52) | RXRAMAPTKARS1NPC1RAB9A | |
| SCHEMBL30894571 | 0.77 | RXRA (0.72) | RXRAMAPTNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117645568-A | N- ([ 4,4' -bipyridine ] -2-yl) cinnamamide derivative, and preparation and application thereof | 厦门大学 | 2024-03-05 | — | — | CN | disclosed |