Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.47 |
| ▸ | RELA | Q04206 | 2/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27253849 | 1.00 | ALOX15 (0.51) | ALOX15HSD17B10CYP2C9KDM4EALDH1A1 | |
| SCHEMBL27253851 | 0.82 | KMT2A (0.46) | ALOX15KDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL27253852 | 0.81 | KDM4E (0.54) | ALOX15KDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL27253850 | 0.80 | L3MBTL1 (0.48) | ALOX15HSD17B10CYP2C9KDM4EALDH1A1 | |
| SCHEMBL12530911 | 0.80 | HSD17B10 (0.60) | ALOX15HSD17B10CYP2C9KDM4EALDH1A1 | |
| SCHEMBL5594626 | 0.78 | KDM4E (0.75) | ALOX15KDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL18209437 | 0.74 | CYP2C9 (0.64) | ALOX15HSD17B10CYP2C9KDM4EALDH1A1 | |
| SCHEMBL2525228 | 0.72 | KMT2A (0.61) | ALOX15HSD17B10KDM4EALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL30894755 | 0.71 | KMT2A (0.59) | ALOX15HSD17B10KDM4EALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL11130882 | 0.71 | KMT2A (0.59) | ALOX15HSD17B10KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4622962-A1 | SMALL MOLECULAR WEIGHT CHEMICAL COMPOUND TO ANTAGONIZE EPH-EPHRIN TETRAMERIZATION AND INHIBIT BIDIRECTIONAL SIGNALING | The Board of Regents of the University of Texas System (US) | 2025-10-01 | — | — | EP | disclosed |
| WO-2024092083-A1 | SMALL MOLECULAR WEIGHT CHEMICAL COMPOUND TO ANTAGONIZE EPH-EPHRIN TETRAMERIZATION AND INHIBIT BIDIRECTIONAL SIGNALING | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2024-05-02 | — | — | WO | disclosed |