Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30895708 | 0.83 | KDM4C (0.42) | KDM4CPARP1ALDH1A1LMNAALPL | |
| SCHEMBL20544984 | 0.82 | ALDH1A1 (0.45) | KDM4CALDH1A1LMNAKDM4ESTAT3 | |
| SCHEMBL28662611 | 0.77 | ALDH1A1 (0.42) | KDM4CALDH1A1LMNAKDM4EHIF1A | |
| SCHEMBL20545378 | 0.76 | AHR (0.46) | KDM4CALDH1A1LMNAALPLKDM4E | |
| SCHEMBL3406540 | 0.74 | KDM4E (0.53) | KDM4CALDH1A1LMNAALPLKDM4E | |
| SCHEMBL2862825 | 0.73 | KDM4E (0.59) | KDM4CLMNAALPLKDM4ESTAT3 | |
| SCHEMBL27242667 | 0.70 | MAP2K4 (0.48) | KDM4CPARP1ALDH1A1LMNAALPL | |
| SCHEMBL2730590 | 0.69 | MAPT (0.48) | ALDH1A1LMNAKDM4EMAPTKMT2A | |
| SCHEMBL16832920 | 0.68 | NQO2 (0.54) | PARP1KDM4EMAPTKMT2AGAA | |
| SCHEMBL28100577 | 0.68 | TACR3 (0.43) | PARP1ALDH1A1KDM4EMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4385980-A1 | INDAZOLES AS INHIBITORS OF NAV1.8 | Grünenthal GmbH (DE) | 2024-06-19 | — | — | EP | disclosed |