Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ILK | Q13418 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20544984 | 0.83 | ALDH1A1 (0.45) | KDM4CALDH1A1LMNAELANEKDM4E | |
| SCHEMBL30895705 | 0.83 | KDM4C (0.41) | KDM4CPARP1ALDH1A1LMNAKDM4E | |
| SCHEMBL28662611 | 0.79 | ALDH1A1 (0.42) | KDM4CALDH1A1LMNAKDM4EHIF1A | |
| SCHEMBL3406540 | 0.76 | KDM4E (0.53) | KDM4CALDH1A1LMNANR4A2KDM4E | |
| SCHEMBL27387337 | 0.67 | PARP1 (0.44) | PARP1ELANE | |
| SCHEMBL2907070 | 0.67 | MAPT (0.52) | PARP1ALDH1A1LMNAELANEKDM4E | |
| SCHEMBL16832355 | 0.67 | NQO2 (0.56) | PARP1ALDH1A1NR4A2ELANEKDM4E | |
| SCHEMBL27242596 | 0.67 | KDM4E (0.62) | KDM4CALDH1A1NR4A2ELANEKDM4E | |
| SCHEMBL29146919 | 0.66 | KDM4E (0.46) | KDM4CPARP1ALDH1A1NR4A2KDM4E | |
| SCHEMBL7646329 | 0.66 | KMT2A (0.52) | ALDH1A1KDM4EMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4385980-A1 | INDAZOLES AS INHIBITORS OF NAV1.8 | Grünenthal GmbH (DE) | 2024-06-19 | — | — | EP | disclosed |