Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORT1 | Q99523 | 3/20 | 0.37 |
| ▸ | RBP4 | P02753 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 2/20 | 0.35 |
| ▸ | GRM8 | O00222 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MYC | P01106 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31619676 | 0.89 | NPC1 (0.36) | KDM4EPDE4BGRM8CYP1A2CYP2C9 | |
| SCHEMBL30895805 | 0.85 | KDM4E (0.39) | KDM4ETDP1L3MBTL1MAPTLMNA | |
| SCHEMBL30895831 | 0.85 | KDM4E (0.39) | KDM4ETDP1L3MBTL1MAPTLMNA | |
| SCHEMBL30895826 | 0.83 | SORT1 (0.43) | SORT1KDM4ETDP1L3MBTL1MAPT | |
| SCHEMBL25308308 | 0.78 | AURKA (0.42) | KDM4EMEN1KMT2APOLBHTT | |
| SCHEMBL25153563 | 0.77 | POLQ (0.41) | KDM4ELMNAMEN1KMT2A | |
| SCHEMBL30282798 | 0.77 | POLQ (0.41) | KDM4ELMNAMEN1KMT2A | |
| SCHEMBL25306952 | 0.75 | ALDH1A1 (0.43) | KDM4ETDP1L3MBTL1MAPTMEN1 | |
| SCHEMBL25309279 | 0.73 | HSP90AA1 (0.46) | SORT1KDM4EMAPTRORCMEN1 | |
| SCHEMBL25308518 | 0.73 | DHODH (0.53) | KDM4ETDP1L3MBTL1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120152972-A | Thiadiazole derivative, composition and application thereof | 北京丹擎医药科技有限公司 | 2025-06-13 | — | — | CN | disclosed |
| WO-2024099336-A1 | THIADIAZOLYL DERIVATIVES, COMPOSITIONS AND USES THEREOF | DANATLAS PHARMACEUTICALS CO., LTD. (CN) | 2024-05-16 | — | — | WO | disclosed |