Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CTSA | P10619 | 3/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | ACLY | P53396 | 1/20 | 0.36 |
| ▸ | NEK2 | P51955 | 2/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | FABP3 | P05413 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30895831 | 0.90 | KDM4E (0.39) | KDM4ETDP1L3MBTL1LMNAMAPK1 | |
| SCHEMBL30895826 | 0.87 | SORT1 (0.43) | KDM4ETDP1L3MBTL1LMNAMAPK1 | |
| SCHEMBL30895763 | 0.85 | SORT1 (0.37) | KDM4ETDP1L3MBTL1LMNAMAPK1 | |
| SCHEMBL25308308 | 0.84 | AURKA (0.42) | KDM4EHTTCTSADHODHALDH1A1 | |
| SCHEMBL25306952 | 0.78 | ALDH1A1 (0.43) | KDM4ETDP1L3MBTL1HTTMAPT | |
| SCHEMBL25308518 | 0.76 | DHODH (0.53) | KDM4ETDP1L3MBTL1LMNAMAPK1 | |
| SCHEMBL25309279 | 0.76 | HSP90AA1 (0.46) | KDM4EHTTMAPTCTSAALDH1A1 | |
| SCHEMBL30895810 | 0.74 | POLQ (0.46) | LMNAMAPK1HTTRAB9ACTSA | |
| SCHEMBL31619676 | 0.74 | NPC1 (0.36) | KDM4ERAB9A | |
| SCHEMBL25309836 | 0.73 | KDM4E (0.43) | KDM4ECTSAALDH1A1POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120152972-A | Thiadiazole derivative, composition and application thereof | 北京丹擎医药科技有限公司 | 2025-06-13 | — | — | CN | disclosed |
| WO-2024099336-A1 | THIADIAZOLYL DERIVATIVES, COMPOSITIONS AND USES THEREOF | DANATLAS PHARMACEUTICALS CO., LTD. (CN) | 2024-05-16 | — | — | WO | disclosed |