Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 6/20 | 0.65 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.63 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.62 |
| ▸ | PAK4 | O96013 | 2/20 | 0.57 |
| ▸ | CTSV | O60911 | 1/20 | 0.56 |
| ▸ | PLAT | P00750 | 1/20 | 0.56 |
| ▸ | CTSL | P07711 | 1/20 | 0.56 |
| ▸ | CTSH | P09668 | 1/20 | 0.56 |
| ▸ | CTSS | P25774 | 1/20 | 0.56 |
| ▸ | CASP14 | P31944 | 1/20 | 0.56 |
| ▸ | CTSK | P43235 | 1/20 | 0.56 |
| ▸ | CASP6 | P55212 | 1/20 | 0.56 |
| ▸ | CTSZ | Q9UBR2 | 1/20 | 0.56 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.54 |
| ▸ | PDE5A | O76074 | 3/20 | 0.53 |
| ▸ | ACP1 | P24666 | 1/20 | 0.53 |
| ▸ | OGG1 | O15527 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27223336 | 1.00 | MERTK (0.65) | MERTKNPY5RCAMK2DPAK4CTSV | |
| SCHEMBL5805116 | 0.91 | CAMK2D (0.74) | MERTKNPY5RCAMK2DPDE5AACP1 | |
| SCHEMBL27223939 | 0.91 | CAMK2D (0.74) | MERTKNPY5RCAMK2DPDE5AACP1 | |
| SCHEMBL27224037 | 0.90 | CAMK2D (0.76) | MERTKNPY5RCAMK2DPDE5AACP1 | |
| SCHEMBL27224044 | 0.88 | MERTK (0.81) | MERTKNPY5RPDE5AACP1OGG1 | |
| SCHEMBL27223364 | 0.87 | MERTK (0.76) | MERTKNPY5RCAMK2DPDE5AACP1 | |
| SCHEMBL30896246 | 0.86 | MERTK (0.65) | MERTKNPY5RCAMK2DSOS1PDE5A | |
| SCHEMBL27224015 | 0.86 | MERTK (0.65) | MERTKNPY5RCAMK2DSOS1PDE5A | |
| SCHEMBL27223511 | 0.86 | MERTK (0.75) | MERTKNPY5RPAK4PDE5AACP1 | |
| SCHEMBL27223499 | 0.86 | MERTK (0.68) | MERTKNPY5RCAMK2DSOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240166626-A1 | Compounds and Methods for Preventing, Treating, or Ameliorating Airway Disease | UNIV JEFFERSON (US) | 2024-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240166626-A1 | Compounds and Methods for Preventing, Treating, or Ameliorating Airway Disease | ADRB2, ADRB1, ADRB3 | MERTK 3423/4885NPY5R 2011/4885CAMK2D 389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.