Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.54 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.54 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.46 |
| ▸ | MELK | Q14680 | 2/20 | 0.45 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.36 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.36 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6042697 | 1.00 | CYP19A1 (0.54) | CYP19A1TBXAS1PRKCZMELKCCNT1 | |
| SCHEMBL6947317 | 0.92 | CYP19A1 (0.54) | CYP19A1TBXAS1PRKCZMELKCCNT1 | |
| SCHEMBL29612558 | 0.92 | CYP19A1 (0.54) | CYP19A1TBXAS1PRKCZMELKCCNT1 | |
| Bromide SCHEMBL6042233 | 0.90 | CYP19A1 (0.53) | CYP19A1TBXAS1PRKCZMELKCCNT1 | |
| SCHEMBL27409209 | 0.85 | CYP19A1 (0.51) | CYP19A1TBXAS1PRKCZMELKCCNT1 | |
| SCHEMBL3821797 | 0.80 | CYP19A1 (0.54) | CYP19A1TBXAS1PRKCZMELKMRGPRX4 | |
| SCHEMBL3153982 | 0.80 | CYP19A1 (0.54) | CYP19A1TBXAS1PRKCZMELKHASPIN | |
| SCHEMBL5779124 | 0.80 | MELK (0.55) | CYP19A1TBXAS1PRKCZMELKIKBKB | |
| SCHEMBL6897234 | 0.80 | CYP19A1 (0.54) | CYP19A1TBXAS1PRKCZMELKMRGPRX4 | |
| SCHEMBL6114863 | 0.80 | CYP1A2 (0.55) | CYP19A1TBXAS1PRKCZMELKMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117980292-A | Substituted pyridone compounds for the treatment of orthomyxoviral infections | 诺华股份有限公司 | 2024-05-03 | — | — | CN | disclosed |