Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL1 | P55085 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | PKLR | P30613 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2004077 | 0.86 | NPC1 (0.32) | NPC1 | |
| SCHEMBL4718604 | 0.80 | TDP1 (0.37) | NPC1 | |
| SCHEMBL25368727 | 0.80 | DGAT1 (0.41) | F2RL1DGAT1NPC1 | |
| SCHEMBL29493823 | 0.80 | DGAT1 (0.41) | F2RL1DGAT1NPC1 | |
| SCHEMBL30896329 | 0.79 | HPGD (0.39) | NPC1 | |
| SCHEMBL25368440 | 0.78 | DGAT1 (0.41) | F2RL1DGAT1NPC1 | |
| SCHEMBL28991115 | 0.75 | BRD4 (0.39) | F2RL1DGAT1BRD4 | |
| SCHEMBL12175756 | 0.75 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL3516228 | 0.74 | GLS (0.57) | NPC1PKM | |
| SCHEMBL2000722 | 0.73 | ALDH1A1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4612128-A1 | COMPOUNDS AND THEIR USE FOR TREATMENT OF HEMOGLOBINOPATHIES | Bristol-Myers Squibb Company (US) | 2025-09-10 | — | — | EP | disclosed |
| CN-120129677-A | Compounds and their use for the treatment of heme lesions | 百时美施贵宝公司 | 2025-06-10 | — | — | CN | disclosed |
| WO-2024097932-A1 | COMPOUNDS AND THEIR USE FOR TREATMENT OF HEMOGLOBINOPATHIES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-05-10 | — | — | WO | disclosed |