Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 17/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 17/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31714299 | 0.85 | ATAD2 (0.50) | MAPK1CYP11B1CYP11B2CYP19A1CYP3A4 | |
| SCHEMBL31714397 | 0.85 | MAPK1 (0.43) | MAPK1BRD4 | |
| SCHEMBL31714434 | 0.84 | MAPK1 (0.43) | MAPK1CYP11B1CYP11B2CYP19A1CYP3A4 | |
| SCHEMBL31714626 | 0.81 | PDE3B (0.38) | MAPK1BRD4 | |
| SCHEMBL31714295 | 0.80 | MAPT (0.42) | MAPK1BRD4 | |
| SCHEMBL31714283 | 0.80 | OTUD7B (0.35) | MAPK1BRD4 | |
| SCHEMBL31714708 | 0.79 | MAPK1 (0.38) | MAPK1CYP11B2 | |
| SCHEMBL31714444 | 0.79 | CYP11B2 (0.44) | CYP11B1CYP11B2 | |
| SCHEMBL31714584 | 0.77 | MAPK1 (0.43) | MAPK1CYP11B1CYP11B2CYP19A1CYP3A4 | |
| SCHEMBL30896345 | 0.77 | CYP11B1 (0.39) | CYP11B1CYP11B2CYP19A1CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4612128-A1 | COMPOUNDS AND THEIR USE FOR TREATMENT OF HEMOGLOBINOPATHIES | Bristol-Myers Squibb Company (US) | 2025-09-10 | — | — | EP | disclosed |
| CN-120129677-A | Compounds and their use for the treatment of heme lesions | 百时美施贵宝公司 | 2025-06-10 | — | — | CN | disclosed |
| WO-2024097932-A1 | COMPOUNDS AND THEIR USE FOR TREATMENT OF HEMOGLOBINOPATHIES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-05-10 | — | — | WO | disclosed |