Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | LEF1 | Q9UJU2 | 1/20 | 0.38 |
| ▸ | CALCRL | Q16602 | 3/20 | 0.38 |
| ▸ | NR1I3 | Q14994 | 4/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | B3GNT2 | Q9NY97 | 2/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12207033 | 0.81 | PSMB8 (0.49) | ACSS2CA12CA1CA9LEF1 | |
| SCHEMBL20529229 | 0.75 | KDM4E (0.50) | B3GNT2PSMB8 | |
| SCHEMBL21635682 | 0.74 | ALDH1A1 (0.41) | CA12CA1CA9 | |
| SCHEMBL20529269 | 0.72 | B3GNT2 (0.64) | B3GNT2MAOB | |
| SCHEMBL15337817 | 0.71 | DAO (0.55) | CALCRLB3GNT2ARMAOB | |
| SCHEMBL12207055 | 0.71 | SMN1; SMN2 (0.55) | CA12CA1CA9LEF1PSMB8 | |
| SCHEMBL20529240 | 0.71 | MAOB (0.44) | B3GNT2ARMAOB | |
| SCHEMBL31701806 | 0.70 | AKT2 (0.42) | B3GNT2ARMAOB | |
| SCHEMBL22716842 | 0.68 | PGR (0.50) | CA12CA9B3GNT2 | |
| SCHEMBL23997292 | 0.68 | HDAC1 (0.45) | RXFP1B3GNT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024078569-A1 | AROMATIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 浙江海正药业股份有限公司 | 2024-04-18 | — | — | WO | disclosed |