Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDC1 | Q96MU7 | 8/20 | 0.51 |
| ▸ | YTHDF3 | Q7Z739 | 2/20 | 0.47 |
| ▸ | YTHDF1 | Q9BYJ9 | 2/20 | 0.47 |
| ▸ | YTHDF2 | Q9Y5A9 | 2/20 | 0.47 |
| ▸ | METAP2 | P50579 | 2/20 | 0.45 |
| ▸ | METAP1 | P53582 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.37 |
| ▸ | CDK2 | P24941 | 3/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30898248 | 0.81 | YTHDC1 (0.56) | YTHDC1YTHDF3YTHDF1YTHDF2SMN1; SMN2 | |
| SCHEMBL30898259 | 0.76 | YTHDC1 (0.51) | YTHDC1YTHDF3YTHDF1YTHDF2XDH | |
| SCHEMBL30898239 | 0.75 | YTHDC1 (0.50) | YTHDC1YTHDF3YTHDF1YTHDF2SMN1; SMN2 | |
| SCHEMBL30898203 | 0.68 | YTHDC1 (0.50) | YTHDC1YTHDF3YTHDF1YTHDF2 | |
| SCHEMBL22131187 | 0.66 | YTHDC1 (0.45) | YTHDC1YTHDF3YTHDF1YTHDF2METAP2 | |
| SCHEMBL16200073 | 0.66 | METAP1 (0.44) | METAP2METAP1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL16094334 | 0.65 | YTHDC1 (0.61) | YTHDC1YTHDF3YTHDF1YTHDF2ALOX15 | |
| SCHEMBL13162523 | 0.64 | LRRK2 (0.53) | METAP2METAP1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL17971630 | 0.64 | METAP1 (0.56) | METAP2METAP1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL14041138 | 0.62 | SMN1; SMN2 (0.66) | METAP2METAP1SMN1; SMN2KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024105159-A1 | LIGANDS OF THE M6A-RNA READERS | UNIVERSITY OF ZURICH (CH) | 2024-05-23 | — | — | WO | disclosed |