SCHEMBL30898239

SCHEMBL30898239

CNc1nc(Cl)nc2c(-c3cccnc3)[nH]nc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
YTHDC1 Q96MU7 4/20 0.50
YTHDF3 Q7Z739 2/20 0.46
YTHDF1 Q9BYJ9 2/20 0.46
YTHDF2 Q9Y5A9 2/20 0.46
CYP3A4 P08684 5/20 0.40
CYP1A2 P05177 4/20 0.40
CYP2D6 P10635 2/20 0.40
CYP2C9 P11712 2/20 0.40
CYP2C19 P33261 2/20 0.40
HSD17B10 Q99714 1/20 0.40
CLK4 Q9HAZ1 1/20 0.40
CYP2A6 P11509 2/20 0.37
CYP2E1 P05181 1/20 0.37
CYP2B6 P20813 1/20 0.37
ALK Q9UM73 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.36
PIM1 P11309 1/20 0.35
ALDH1A1 P00352 2/20 0.35
MKNK1 Q9BUB5 1/20 0.35
MKNK2 Q9HBH9 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30898248 0.85 YTHDC1 (0.56) YTHDC1YTHDF3YTHDF1YTHDF2HSD17B10
SCHEMBL30898181 0.75 YTHDC1 (0.51) YTHDC1YTHDF3YTHDF1YTHDF2HSD17B10
SCHEMBL30898203 0.74 YTHDC1 (0.50) YTHDC1YTHDF3YTHDF1YTHDF2PIM1
SCHEMBL16670756 0.72 CYP2A6 (0.42) CYP3A4CYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL30898259 0.70 YTHDC1 (0.51) YTHDC1YTHDF3YTHDF1YTHDF2
SCHEMBL14358613 0.68 CLK4 (0.53) CYP3A4CYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL16183454 0.68 TRIM58 (0.53) CYP3A4CYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL28021139 0.65 IDO1 (0.54) CYP3A4CYP1A2CYP2A6CYP2E1CYP2B6
SCHEMBL16094334 0.64 YTHDC1 (0.61) YTHDC1YTHDF3YTHDF1YTHDF2CYP1A2
SCHEMBL16670591 0.64 CYP1A2 (0.40) CYP3A4CYP1A2CYP2D6CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024105159-A1 LIGANDS OF THE M6A-RNA READERS UNIVERSITY OF ZURICH (CH) 2024-05-23 WO disclosed