SCHEMBL30898232

SCHEMBL30898232

CNc1nc(Cl)nc2c(Cc3cccc(Cl)c3)[nH]nc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
YTHDC1 Q96MU7 10/20 1.00
YTHDF3 Q7Z739 2/20 1.00
YTHDF1 Q9BYJ9 2/20 1.00
YTHDF2 Q9Y5A9 2/20 1.00
TMIGD3 P0DMS9 1/20 0.43
HTR2C P28335 1/20 0.43
HTR2B P41595 1/20 0.43
PDE5A O76074 1/20 0.42
PDE9A O76083 1/20 0.42
PDE1A P54750 1/20 0.42
PDE1B Q01064 1/20 0.42
PDE1C Q14123 1/20 0.42
PDE2A O00408 1/20 0.41
MPO P05164 1/20 0.39
GRM4 Q14833 1/20 0.39
HCAR2 Q8TDS4 1/20 0.39
TAAR1 Q96RJ0 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27387656 1.00 YTHDC1 (1.00) YTHDC1YTHDF3YTHDF1YTHDF2TMIGD3
SCHEMBL30898260 0.88 YTHDC1 (0.78) YTHDC1YTHDF3YTHDF1YTHDF2MPO
SCHEMBL30898225 0.85 YTHDC1 (0.73) YTHDC1YTHDF3YTHDF1YTHDF2MPO
SCHEMBL30898254 0.84 YTHDC1 (0.72) YTHDC1YTHDF3YTHDF1YTHDF2HTR2B
SCHEMBL30898241 0.77 YTHDC1 (0.62) YTHDC1YTHDF3YTHDF1YTHDF2PDE2A
SCHEMBL30898280 0.72 YTHDF3 (0.56) YTHDC1YTHDF3YTHDF1YTHDF2PDE5A
SCHEMBL30898226 0.69 YTHDC1 (0.55) YTHDC1YTHDF3YTHDF1YTHDF2
SCHEMBL27387505 0.68 YTHDC1 (1.00) YTHDC1
SCHEMBL30898248 0.68 YTHDC1 (0.56) YTHDC1YTHDF3YTHDF1YTHDF2
SCHEMBL30898272 0.67 YTHDC1 (0.51) YTHDC1YTHDF3YTHDF1YTHDF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024105159-A1 LIGANDS OF THE M6A-RNA READERS UNIVERSITY OF ZURICH (CH) 2024-05-23 WO disclosed