Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDF3 | Q7Z739 | 2/20 | 0.56 |
| ▸ | YTHDC1 | Q96MU7 | 2/20 | 0.56 |
| ▸ | YTHDF1 | Q9BYJ9 | 2/20 | 0.56 |
| ▸ | YTHDF2 | Q9Y5A9 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.38 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | PDE9A | O76083 | 1/20 | 0.35 |
| ▸ | PDE1A | P54750 | 1/20 | 0.35 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.35 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.35 |
| ▸ | MAT2A | P31153 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30898217 | 0.78 | ALDH1A1 (0.42) | MAPTCSF1REGFRALDH1A1 | |
| SCHEMBL30898234 | 0.73 | MAPT (0.36) | TP53MAPTTAS2R14BCL2A1CSF1R | |
| SCHEMBL27387656 | 0.72 | YTHDC1 (1.00) | YTHDF3YTHDC1YTHDF1YTHDF2PDE5A | |
| SCHEMBL30898232 | 0.72 | YTHDC1 (1.00) | YTHDF3YTHDC1YTHDF1YTHDF2PDE5A | |
| SCHEMBL28242199 | 0.68 | LTA4H (0.63) | TP53MAPTTAS2R14ALDH1A1KMT2A | |
| SCHEMBL3113190 | 0.67 | EGFR (0.67) | MAPTCSF1REGFRALDH1A1PDE5A | |
| SCHEMBL30898283 | 0.66 | DHFR (0.41) | ALDH1A1KMT2A | |
| SCHEMBL30898254 | 0.63 | YTHDC1 (0.72) | YTHDF3YTHDC1YTHDF1YTHDF2ADORA2A | |
| SCHEMBL30898260 | 0.62 | YTHDC1 (0.78) | YTHDF3YTHDC1YTHDF1YTHDF2 | |
| SCHEMBL3112339 | 0.62 | GBA1 (0.67) | MAPTCSF1REGFRALDH1A1PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024105159-A1 | LIGANDS OF THE M6A-RNA READERS | UNIVERSITY OF ZURICH (CH) | 2024-05-23 | — | — | WO | disclosed |