Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS4 | O75173 | 8/20 | 0.60 |
| ▸ | MMP12 | P39900 | 8/20 | 0.60 |
| ▸ | ADAMTS5 | Q9UNA0 | 8/20 | 0.60 |
| ▸ | MMP2 | P08253 | 7/20 | 0.60 |
| ▸ | MMP3 | P08254 | 7/20 | 0.60 |
| ▸ | MMP13 | P45452 | 7/20 | 0.60 |
| ▸ | MMP14 | P50281 | 7/20 | 0.60 |
| ▸ | MMP1 | P03956 | 5/20 | 0.59 |
| ▸ | MMP9 | P14780 | 4/20 | 0.59 |
| ▸ | MMP7 | P09237 | 1/20 | 0.59 |
| ▸ | MMP8 | P22894 | 4/20 | 0.58 |
| ▸ | ADAMTS7 | Q9UKP4 | 9/20 | 0.56 |
| ▸ | NAMPT | P43490 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24182498 | 1.00 | ADAMTS4 (0.60) | ADAMTS4MMP12ADAMTS5MMP2MMP3 | |
| SCHEMBL24182499 | 0.85 | ADAMTS5 (0.49) | ADAMTS4MMP12ADAMTS5MMP2MMP3 | |
| SCHEMBL24182495 | 0.84 | ADAMTS5 (0.48) | ADAMTS4MMP12ADAMTS5MMP2MMP3 | |
| SCHEMBL29835134 | 0.84 | ADAMTS5 (0.55) | ADAMTS4ADAMTS5MMP2MMP13 | |
| SCHEMBL29250257 | 0.84 | ADAMTS5 (0.55) | ADAMTS4ADAMTS5MMP2MMP13 | |
| SCHEMBL23745214 | 0.84 | ADAMTS5 (0.55) | ADAMTS4ADAMTS5MMP2MMP13 | |
| SCHEMBL24182490 | 0.83 | ADAMTS7 (0.49) | ADAMTS4MMP12ADAMTS5MMP2MMP3 | |
| SCHEMBL24182483 | 0.83 | ADAMTS7 (0.49) | ADAMTS4MMP12ADAMTS5MMP2MMP3 | |
| SCHEMBL24182482 | 0.83 | ADAMTS7 (0.49) | ADAMTS4MMP12ADAMTS5MMP2MMP3 | |
| SCHEMBL24182494 | 0.82 | ADAMTS4 (0.48) | ADAMTS4MMP12ADAMTS5MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113754635-B | Condensed ring compound and preparation method and application thereof | 成都康弘药业集团股份有限公司 | 2024-06-21 | — | — | CN | disclosed |