Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 2/20 | 0.59 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.53 |
| ▸ | IDO1 | P14902 | 4/20 | 0.52 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.48 |
| ▸ | HTR3B | O95264 | 2/20 | 0.48 |
| ▸ | HTR3A | P46098 | 2/20 | 0.48 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.48 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8238578 | 1.00 | PNMT (0.59) | PNMTTAAR1IDO1HTR3EHTR3B | |
| Hydrochloric Acid SCHEMBL15863064 | 0.98 | PNMT (0.57) | PNMTTAAR1IDO1HTR3EHTR3B | |
| SCHEMBL2944420 | 0.85 | PKM (0.64) | PNMTTAAR1IDO1HTR3EHTR3B | |
| Hydrochloric Acid SCHEMBL3244563 | 0.83 | PKM (0.62) | PNMTTAAR1IDO1HTR3EHTR3B | |
| SCHEMBL3395963 | 0.79 | PKM (0.74) | PNMTTAAR1IDO1HTR3EHTR3B | |
| SCHEMBL3393837 | 0.79 | PNMT (0.59) | PNMTTAAR1IDO1LMNASMN1; SMN2 | |
| SCHEMBL29760897 | 0.79 | PNMT (0.59) | PNMTTAAR1IDO1LMNASMN1; SMN2 | |
| SCHEMBL15866833 | 0.79 | DPP4 (0.58) | PNMTTAAR1IDO1HTR3EHTR3B | |
| SCHEMBL1021475 | 0.78 | AKR1B1 (0.54) | TAAR1IDO1HTR3EHTR3BHTR3A | |
| SCHEMBL11443612 | 0.77 | IDO1 (0.74) | PNMTTAAR1IDO1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4594324-A1 | AZOLE DERIVATIVES AS SHP2 INHIBITORS | IRBM S.P.A. (IT) | 2025-08-06 | — | — | EP | disclosed |
| CN-120129683-A | Azole derivatives as SHP2 inhibitors | IRBM股份公司 | 2025-06-10 | — | — | CN | disclosed |