SCHEMBL21596788

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21596828	0.84	TRPV4 (0.35)	TRPV4ADORA1ADORA2AMEN1ALDH1A1
	SCHEMBL24413387	0.76	TRPV4 (0.54)	TRPV4EGLN2EPAS1VEGFA
	SCHEMBL13863736	0.76	TRPV4 (0.54)	TRPV4EGLN2EPAS1
	SCHEMBL17365726	0.75	GRIN1 (0.34)	MEN1ALDH1A1LMNAHSP90AA1PKM
	SCHEMBL559898	0.75	TRPV4 (0.48)	TRPV4LMNAHTT
	SCHEMBL186585	0.74	TRPV4 (0.52)	TRPV4ADORA1ADORA2AMEN1ALDH1A1
	SCHEMBL29639661	0.72	EPAS1 (0.45)	EPAS1VEGFA
	SCHEMBL24816740	0.72	TRPV4 (0.41)	TRPV4EGLN2
	SCHEMBL18036193	0.72	EGLN2 (0.36)	ADORA1ADORA2AEGLN2
	SCHEMBL31535909	0.72	TRPV4 (0.37)	TRPV4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.