SCHEMBL3090109

SCHEMBL3090109

O=C(O)[C@H](Cc1ccccc1)NCC=CP(=O)(O)O

nearest known ligand 0.45

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.45
MME P08473 1/20 0.44
NPSR1 Q6W5P4 1/20 0.43
FPR2 P25090 6/20 0.43
PTPN1 P18031 2/20 0.43
NAALAD2 Q9Y3Q0 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3082080 0.89 FOLH1 (0.45) L3MBTL1MMENAALAD2
SCHEMBL29661948 0.81 PPARG (0.51) MMENPSR1FPR2
SCHEMBL7452658 0.79 MME (0.51) L3MBTL1MMENPSR1FPR2NAALAD2
SCHEMBL3952722 0.79 MME (0.51) L3MBTL1MMENPSR1FPR2NAALAD2
SCHEMBL3082103 0.78 ALOX15 (0.57) L3MBTL1FPR2
SCHEMBL43351 0.77 MME (0.62) L3MBTL1MMENPSR1
SCHEMBL972349 0.77 MME (0.50) L3MBTL1MMENPSR1FPR2NAALAD2
SCHEMBL972348 0.77 MME (0.50) L3MBTL1MMENPSR1FPR2NAALAD2
SCHEMBL43350 0.77 MME (0.62) L3MBTL1MMENPSR1
SCHEMBL3082704 0.77 TGFBR1 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100247463-A1 N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE YU RUEY J 2010-09-30 US disclosed
US-7776844-B2 N-(phosphonoalkyl)-amino acids, derivatives thereof and compositions and methods of use YU RUEY J 2010-08-17 US disclosed
US-20090208499-A1 N-(Phosphonoalkyl)-Amino Acids, Derivatives Thereof and Compositions and Methods of Use YU RUEY J 2009-08-20 US disclosed
US-7572776-B2 N-(phosphonoalkyl)-amino acids, derivatives thereof and compositions and methods of use YU RUEY J 2009-08-11 US disclosed
US-20080306025-A1 N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE YU RUEY J 2008-12-11 US disclosed
EP-1979366-A2 N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE Yu, Ruey J. (US) 2008-10-15 EP disclosed
US-7429575-B2 N-(phosphonoalkyl)-amino acids, derivatives thereof and compositions and methods of use YU RUEY J 2008-09-30 US disclosed
WO-2007082206-A2 N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE YU RUEY J (US) 2007-07-19 WO disclosed
US-20070161543-A1 N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE YU RUEY J 2007-07-12 US disclosed