Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 2/20 | 0.53 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.53 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.51 |
| ▸ | NTSR1 | P30989 | 6/20 | 0.49 |
| ▸ | NTSR2 | O95665 | 3/20 | 0.49 |
| ▸ | APLNR | P35414 | 1/20 | 0.49 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.48 |
| ▸ | MC4R | P32245 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 4/20 | 0.48 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 2/20 | 0.47 |
| ▸ | CTSS | P25774 | 2/20 | 0.47 |
| ▸ | CTSK | P43235 | 2/20 | 0.47 |
| ▸ | CTSH | P09668 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30901125 | 0.90 | AGTR2 (0.47) | AGTR2AGTR1C5AR1NTSR1NTSR2 | |
| SCHEMBL29701256 | 0.90 | AGTR2 (0.65) | AGTR2AGTR1C5AR1NTSR1NTSR2 | |
| SCHEMBL29701258 | 0.90 | AGTR2 (0.55) | AGTR2AGTR1C5AR1NTSR1NTSR2 | |
| Talfirastide SCHEMBL15926158 | 0.90 | AGTR1 (0.59) | AGTR2AGTR1C5AR1NTSR1NTSR2 | |
| SCHEMBL7052378 | 0.89 | AGTR2 (0.65) | AGTR2AGTR1C5AR1NTSR1NTSR2 | |
| SCHEMBL29972916 | 0.88 | AGTR1 (0.62) | AGTR2AGTR1C5AR1NTSR1NTSR2 | |
| Angiotensin Ii SCHEMBL9013950 | 0.88 | AGTR2 (0.69) | AGTR2AGTR1C5AR1NTSR1NTSR2 | |
| Angiotensin Ii SCHEMBL22125774 | 0.88 | AGTR2 (0.69) | AGTR2AGTR1C5AR1NTSR1NTSR2 | |
| Angiotensin Ii SCHEMBL29757879 | 0.88 | AGTR2 (0.69) | AGTR2AGTR1C5AR1NTSR1NTSR2 | |
| Angiotensin Ii SCHEMBL9013957 | 0.88 | AGTR2 (0.69) | AGTR2AGTR1C5AR1NTSR1NTSR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4371556-A1 | ANGIOTENSIN(1-7) PHARMACEUTICAL COMPOSITIONS FOR INHALATION | Explicat Pharma GmbH (DE) | 2024-05-22 | — | — | EP | disclosed |