Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.49 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 3/20 | 0.47 |
| ▸ | CTSS | P25774 | 3/20 | 0.47 |
| ▸ | CTSK | P43235 | 3/20 | 0.47 |
| ▸ | CTSH | P09668 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.45 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.45 |
| ▸ | APLNR | P35414 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.44 |
| ▸ | CALCR | P30988 | 4/20 | 0.44 |
| ▸ | MC4R | P32245 | 1/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.42 |
| ▸ | NPY2R | P49146 | 1/20 | 0.42 |
| ▸ | NPY4R | P50391 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30901125 | 0.94 | AGTR2 (0.47) | AGTR1AGTR2CTSLCTSSCTSK | |
| Talfirastide SCHEMBL15926158 | 0.92 | AGTR1 (0.59) | AGTR1AGTR2EPHA2C5AR1APLNR | |
| SCHEMBL14921065 | 0.91 | C5AR1 (0.49) | CTSLCTSSCTSKCTSHC5AR1 | |
| SCHEMBL29701258 | 0.89 | AGTR2 (0.55) | AGTR1AGTR2EPHA2C5AR1APLNR | |
| Angiotensin-Ii SCHEMBL29973063 | 0.88 | AGTR2 (0.62) | AGTR1AGTR2EPHA2C5AR1APLNR | |
| SCHEMBL29972916 | 0.87 | AGTR1 (0.62) | AGTR1AGTR2EPHA2C5AR1CALCR | |
| SCHEMBL9510693 | 0.87 | AGTR1 (0.60) | AGTR1AGTR2EPHA2C5AR1CALCR | |
| SCHEMBL29602954 | 0.87 | C5AR1 (0.55) | AGTR1AGTR2C5AR1 | |
| SCHEMBL15928128 | 0.87 | AGTR2 (0.59) | AGTR1AGTR2C5AR1CALCR | |
| SCHEMBL7052378 | 0.86 | AGTR2 (0.65) | AGTR1AGTR2EPHA2C5AR1APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4371556-A1 | ANGIOTENSIN(1-7) PHARMACEUTICAL COMPOSITIONS FOR INHALATION | Explicat Pharma GmbH (DE) | 2024-05-22 | — | — | EP | disclosed |