SCHEMBL30901136

SCHEMBL30901136

O=S(=O)(F)Oc1ccc2ccc3ccccc3c2c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.49
CA9 Q16790 2/20 0.49
CA2 P00918 1/20 0.49
ALDH1A1 P00352 3/20 0.47
HSD17B10 Q99714 3/20 0.47
HIF1A Q16665 1/20 0.47
CYP1B1 Q16678 1/20 0.47
TDP1 Q9NUW8 3/20 0.43
CYP2A6 P11509 1/20 0.43
TSHR P16473 1/20 0.43
L3MBTL1 Q9Y468 2/20 0.42
GAA P10253 1/20 0.42
MAPK1 P28482 1/20 0.42
LMNA P02545 2/20 0.41
PPARG P37231 1/20 0.41
HTT P42858 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HPRT1 P00492 2/20 0.40
TUBB4A P04350 1/20 0.39
TUBB P07437 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30998117 1.00 CA1 (0.49) CA1CA9CA2ALDH1A1HSD17B10
SCHEMBL15903702 0.85 CA1 (0.52) CA1CA9CA2ALDH1A1HSD17B10
SCHEMBL17318166 0.85 CA1 (0.66) CA1CA9CA2TDP1CYP2A6
SCHEMBL30290794 0.83 CA1 (0.46) CA1CA9CA2ALDH1A1HSD17B10
SCHEMBL29561407 0.82 CA2 (0.49) CA1CA9CA2ALDH1A1HSD17B10
SCHEMBL28069382 0.82 CA2 (0.73) CA1CA9CA2ALDH1A1HSD17B10
SCHEMBL15903703 0.82 GAA (0.49) CA1CA9CA2ALDH1A1HSD17B10
SCHEMBL18346485 0.81 ALDH1A1 (0.36) CA1CA9CA2ALDH1A1HSD17B10
SCHEMBL17233556 0.80 CA2 (0.52) CA1CA9CA2TDP1CYP2A6
SCHEMBL12465666 0.80 HPRT1 (0.44) CA1CA9CA2ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111689929-B Sulfur fluoride (VI) compound and preparation method thereof 斯克里普斯研究所 2024-05-31 CN disclosed