SCHEMBL17318166

SCHEMBL17318166

O=S(=O)(F)Oc1ccc2ccccc2c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.66
CA2 P00918 2/20 0.66
CA9 Q16790 2/20 0.66
TDP1 Q9NUW8 4/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
LMNA P02545 2/20 0.54
PPARG P37231 1/20 0.54
HTT P42858 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
MAPK1 P28482 2/20 0.54
GAA P10253 1/20 0.54
CYP1A2 P05177 2/20 0.48
CYP2A6 P11509 2/20 0.48
GPR84 Q9NQS5 1/20 0.44
AGXT P21549 2/20 0.44
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
ESR1 P03372 1/20 0.43
ATM Q13315 1/20 0.43
ESR2 Q92731 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15779535 0.91 CA2 (0.53) CA1CA2CA9TDP1L3MBTL1
SCHEMBL17233556 0.91 CA2 (0.52) CA1CA2CA9TDP1L3MBTL1
SCHEMBL30901136 0.85 CA1 (0.49) CA1CA2CA9TDP1L3MBTL1
SCHEMBL30998117 0.85 CA1 (0.49) CA1CA2CA9TDP1L3MBTL1
SCHEMBL8320952 0.83 CA1 (0.70) CA1CA2CA9TDP1L3MBTL1
SCHEMBL29839512 0.80 CA1 (0.61) CA1CA2CA9TDP1L3MBTL1
SCHEMBL1713420 0.80 CA1 (0.61) CA1CA2CA9TDP1L3MBTL1
SCHEMBL32665362 0.80 NCEH1 (0.45) CA1CA2CA9TDP1L3MBTL1
SCHEMBL18532783 0.80 NCEH1 (0.45) CA1CA2CA9TDP1L3MBTL1
SCHEMBL32665619 0.80 CA2 (0.43) CA1CA2CA9TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12390424-B2 Sulfur (VI) fluoride compounds and methods for the preparation thereof THE SCRIPPS RESEARCH INSTITUTE (US) 2025-08-19 US disclosed
CN-118047707-A Direct cross coupling method of sulfoxide ylide and aryl fluorosulfonate 南京工业大学 2024-05-17 CN disclosed
EP-4295841-A2 SULFUR (VI) FLUORIDE COMPOUNDS AND THEIR USE IN CLICK-REACTION The Scripps Research Institute (US) 2023-12-27 EP disclosed
EP-3892610-B1 SULFUR (VI) FLUORIDE COMPOUNDS AND THEIR USE IN CLICK-REACTION SCRIPPS RESEARCH INST (US) 2023-08-16 EP disclosed
US-20220313624-A1 SULFUR (VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF THE SCRIPPS RESEARCH INSTITUTE (US) 2022-10-06 US disclosed
US-11230517-B2 Method for aromatic fluorination THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2022-01-25 US disclosed
US-20220000799-A1 SULFUR (VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF THE SCRIPPS RESEARCH INSTITUTE (US) 2022-01-06 US disclosed
EP-3892610-A1 SULFUR (VI) FLUORIDE COMPOUNDS AND THEIR USE AS SCREENING AGENT The Scripps Research Institute (US) 2021-10-13 EP disclosed
US-11141385-B2 Sulfur (VI) fluoride compounds and methods for the preparation thereof THE SCRIPPS RESEARCH INSTITUTE (US) 2021-10-12 US disclosed
EP-3151817-B1 SULFUR(VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF SCRIPPS RESEARCH INST (US) 2021-03-03 EP disclosed
US-20200239390-A1 METHOD FOR AROMATIC FLUORINATION CORTEVA AGRISCIENCE LLC 2020-07-30 US disclosed
EP-3452437-B1 METHOD FOR AROMATIC FLUORINATION DOW GLOBAL TECHNOLOGIES LLC (US) 2020-07-29 EP disclosed
US-10654776-B2 Method for aromatic fluorination DOW GLOBAL TECHNOLOGIES LLC (US) 2020-05-19 US disclosed
US-20190202758-A1 METHOD FOR AROMATIC FLUORINATION CORTEVA AGRISCIENCE LLC 2019-07-04 US disclosed
US-20190029972-A1 SULFUR(VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF THE SCRIPPS RESEARCH INSTITUTE (US) 2019-01-31 US disclosed
US-10117840-B2 Sulfur(VI) fluoride compounds and methods for the preparation thereof THE SCRIPPS RESEARCH INSTITUTE (US) 2018-11-06 US disclosed
WO-2017192564-A1 METHOD FOR AROMATIC FLUORINATION DOW GLOBAL TECHNOLOGIES LLC (US) 2017-11-09 WO disclosed
US-20170196985-A1 SULFUR(VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF THE SCRIPPS RESEARCH INSTITUTE 2017-07-13 US disclosed
EP-3151817-A1 SULFUR(VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF The Scripps Research Institute (US) 2017-04-12 EP disclosed
WO-2015188120-A1 SULFUR(VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF THE SCRIPPS RESEARCH INSTITUTE (US) 2015-12-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200239390-A1 METHOD FOR AROMATIC FLUORINATION ARSA, AHR, AR CA1 3802/4885CA2 1585/4885CA9 2331/4885
US-20170196985-A1 SULFUR(VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF CYP2F1, NAF1, CYP2S1 CA1 228/4885CA2 487/4885CA9 238/4885
US-12390424-B2 Sulfur (VI) fluoride compounds and methods for the preparation thereof GRB2, SCTR, OGFR CA1 128/4885CA2 342/4885CA9 1140/4885
US-20220313624-A1 SULFUR (VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF QSOX1, YBX1, SFXN1 CA1 47/4885CA2 577/4885CA9 964/4885
US-11230517-B2 Method for aromatic fluorination ARSA, AHR, AR CA1 3767/4885CA2 1299/4885CA9 1911/4885
US-20220000799-A1 SULFUR (VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF PTMS, IGF2R, SCTR CA1 129/4885CA2 564/4885CA9 1434/4885
US-20190202758-A1 METHOD FOR AROMATIC FLUORINATION ARSA, AHR, SNRPF CA1 3661/4885CA2 1285/4885CA9 1870/4885
US-20190029972-A1 SULFUR(VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF HAX1, CYP2F1, CYP4X1 CA1 481/4885CA2 504/4885CA9 248/4885
US-10654776-B2 Method for aromatic fluorination ARSA, AHR, SNRPF CA1 3661/4885CA2 1285/4885CA9 1870/4885
US-11141385-B2 Sulfur (VI) fluoride compounds and methods for the preparation thereof CYP2F1, CYP2S1, NAF1 CA1 249/4885CA2 522/4885CA9 193/4885
US-10117840-B2 Sulfur(VI) fluoride compounds and methods for the preparation thereof CYP2F1, NAF1, CYP2S1 CA1 228/4885CA2 487/4885CA9 238/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.