Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 5/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29242486 | 1.00 | DYRK1A (0.54) | DYRK1AALOX5CYP19A1MAOAMAOB | |
| SCHEMBL4400536 | 0.94 | DYRK1A (0.48) | DYRK1AALOX5CYP19A1MAOAMAOB | |
| SCHEMBL5030661 | 0.79 | ALDH1A1 (0.56) | CYP19A1MAOAMAOBPSMB5ESR2 | |
| SCHEMBL4417137 | 0.77 | ESR2 (0.43) | DYRK1AALOX5ESR2MEN1KMT2A | |
| SCHEMBL25107270 | 0.75 | LMNA (0.42) | DYRK1AALOX5MAOAMAOBMEN1 | |
| SCHEMBL14701534 | 0.75 | MEN1 (0.42) | DYRK1ACYP19A1MEN1KMT2AALDH1A1 | |
| SCHEMBL19851151 | 0.75 | MEN1 (0.64) | CYP19A1MAOAMAOBPSMB5ESR2 | |
| SCHEMBL29496707 | 0.74 | MEN1 (0.47) | ALOX5ESR2MEN1KMT2AKDM4E | |
| SCHEMBL918436 | 0.74 | KMT2A (0.61) | DYRK1AESR2MEN1KMT2AKDM4E | |
| SCHEMBL4418128 | 0.74 | ESR2 (0.63) | ALOX5ESR2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117986567-A | Hyperbranched polyaryletherketone and preparation method and application thereof | 中国科学院成都有机化学有限公司 | 2024-05-07 | — | — | CN | disclosed |