Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 18/20 | 0.51 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | DHFR | P00374 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16210658 | 0.83 | TMEM97 (0.52) | PTGDR2TMEM97SIGMAR1DHFR | |
| SCHEMBL16220574 | 0.82 | DHFR (0.50) | PTGDR2TMEM97SIGMAR1DHFR | |
| SCHEMBL16379829 | 0.82 | DHFR (0.50) | PTGDR2TMEM97SIGMAR1DHFR | |
| SCHEMBL15115950 | 0.80 | MEN1 (0.48) | PTGDR2TMEM97SIGMAR1 | |
| SCHEMBL6883527 | 0.80 | GABRA5 (0.49) | PTGDR2TMEM97SIGMAR1 | |
| SCHEMBL16210567 | 0.80 | DHFR (0.48) | PTGDR2TMEM97SIGMAR1DHFR | |
| SCHEMBL3338693 | 0.80 | TMEM97 (0.48) | PTGDR2TMEM97SIGMAR1DHFR | |
| SCHEMBL6490708 | 0.79 | TMEM97 (0.48) | PTGDR2TMEM97SIGMAR1DHFR | |
| SCHEMBL1805209 | 0.77 | KDR (0.49) | PTGDR2TMEM97SIGMAR1DHFR | |
| SCHEMBL6488059 | 0.77 | CLPP (0.52) | PTGDR2TMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250145589-A1 | PYRIDINE DERIVATIVE AND USE THEREOF | SICHUAN HUIYU PHARMACEUTICAL CO., LTD. (CN) | 2025-05-08 | — | — | US | disclosed |
| EP-4406948-A1 | PYRIDINE DERIVATIVE AND USE THEREOF | Sichuan Huiyu Pharmaceutical Co., Ltd. (CN) | 2024-07-31 | — | — | EP | disclosed |
| CN-117957219-A | Pyridine derivative and application thereof | 四川汇宇制药股份有限公司 | 2024-04-30 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250145589-A1 | PYRIDINE DERIVATIVE AND USE THEREOF | KRAS, NRAS, BRAF | PTGDR2 2111/4885TMEM97 3765/4885SIGMAR1 4711/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.