SCHEMBL30902425

SCHEMBL30902425

CCOc1ccc(Cl)cc1CN1CCC(N(C)C)CC1

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.52
HIF1A Q16665 1/20 0.52
RAB9A P51151 1/20 0.50
CCR5 P51681 7/20 0.49
DRD2 P14416 1/20 0.48
DRD4 P21917 1/20 0.48
MAPT P10636 1/20 0.48
CXCR3 P49682 2/20 0.47
NPSR1 Q6W5P4 1/20 0.46
NOS3 P29474 3/20 0.46
NOS1 P29475 3/20 0.46
NOS2 P35228 3/20 0.46
NPY1R P25929 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27340771 1.00 KDM4E (0.52) KDM4EHIF1ARAB9ACCR5DRD2
Succinic Acid SCHEMBL31581209 0.91 DRD2 (0.49) KDM4EHIF1ARAB9ACCR5DRD2
Fumaric Acid SCHEMBL31581190 0.90 DRD2 (0.49) KDM4EHIF1ARAB9ACCR5DRD2
SCHEMBL31581080 0.83 KDM4E (0.60) KDM4EHIF1ARAB9ACCR5DRD2
SCHEMBL30902279 0.81 KDM4E (0.59) KDM4EHIF1ARAB9ACCR5DRD2
SCHEMBL27340760 0.81 KDM4E (0.59) KDM4EHIF1ARAB9ACCR5DRD2
SCHEMBL30902437 0.81 DDR1 (0.46) KDM4EHIF1ARAB9ACCR5DRD2
SCHEMBL16795302 0.79 ALDH1A1 (0.54) KDM4EHIF1AMAPTCXCR3NOS3
Hydrochloric Acid SCHEMBL30902385 0.79 CCR5 (0.52) KDM4EHIF1ARAB9ACCR5DRD2
SCHEMBL27340829 0.78 CCR5 (0.54) KDM4EHIF1ARAB9ACCR5DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4619097-A1 AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF Samsara Therapeutics Inc. (US) 2025-09-24 EP disclosed
WO-2025106477-A1 NOVEL AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF Samsara Therapeutics Inc. (US) 2025-05-22 WO disclosed
WO-2024107434-A1 AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF Samsara Therapeutics Inc. (US) 2024-05-23 WO disclosed