SCHEMBL3090255

SCHEMBL3090255

CCC(CO)(C(=O)O)C(Cl)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28891552 0.88 FFAR3 (0.33)
SCHEMBL11068655 0.77 TP53 (0.32)
SCHEMBL11460744 0.76 LMNA (0.36)
SCHEMBL3554641 0.75 SMPD1 (0.40)
SCHEMBL5566732 0.72 CHRM1 (0.37)
SCHEMBL5608521 0.72 CHRM1 (0.37)
Butyric Acid SCHEMBL4942354 0.71 FFAR3 (0.45)
SCHEMBL11425472 0.70 ALDH1A1 (0.33)
SCHEMBL22202025 0.70 ALDH1A1 (0.33)
SCHEMBL2303259 0.70 ALDH1A1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9677115-B2 Enzyme substrates for visualizing acidic organelles MARKER GENE TECHNOLOGIES, INC. (US) 2017-06-13 US disclosed
US-20130252268-A1 Enzyme substrates for visualizing acidic organelles MARKER GENE TECHNOLOGIES, INC. (US) 2013-09-26 US disclosed
US-8460862-B2 Enzyme substrates for visualizing acidic organelles Marker Gene Technologies (US) 2013-06-11 US disclosed
US-20100233744-A1 Enzyme substrates for visualizing acidic organelles MARKER GENE TECHNOLOGIES, INC. 2010-09-16 US disclosed
EP-1149109-B1 METHOD FOR DEPROTECTING OLIGONUCLEOTIDES GE HEALTHCARE BIO SCIENCES (US) 2009-09-16 EP disclosed
US-6887990-B1 Method for deprotecting oligonucleotides AMERSHAM BIOSCIENCES CORP (US) 2005-05-03 US disclosed
WO-2002051958-A1 ELECTROACTIVE POLYARYLAMINE-TYPE COMPOSITIONS JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2002-07-04 WO disclosed
EP-1149109-A1 METHOD FOR DEPROTECTING OLIGONUCLEOTIDES Amersham Pharmacia Biotech Inc (US) 2001-10-31 EP disclosed
WO-2000046231-A1 METHOD FOR DEPROTECTING OLIGONUCLEOTIDES AMERSHAM PHARMACIA BIOTECH INC. (US) 2000-08-10 WO disclosed
EP-0391594-B1 Cloning genes from streptomyces avermitilis for avermectin biosynthesis and the methods for their use MERCK & CO INC (US) 1995-10-18 EP disclosed
US-5252474-A Cloning genes from Streptomyces avermitilis for avermectin biosynthesis and the methods for their use MERCK & CO., INC. (US) 1993-10-12 US disclosed
EP-0391594-A2 Cloning genes from streptomyces avermitilis for avermectin biosynthesis and the methods for their use MERCK & CO. INC. (US) 1990-10-10 EP disclosed
EP-0223974-A1 N-Substituted-N-[3-(1,2,4-triazolo[4,3-b]pyridazin-6-yl)-phenyl]alkanamides, carbamates and ureas AMERICAN CYANAMID COMPANY (US) 1987-06-03 EP disclosed