Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28571525 | 1.00 | CYP1A1 (0.32) | CYP1A1CYP1A2CYP1B1MEN1ALDH1A1 | |
| SCHEMBL4920144 | 0.73 | CYP1A2 (0.54) | CYP1A1CYP1A2CYP1B1MEN1ALDH1A1 | |
| SCHEMBL30609580 | 0.61 | BCHE (0.51) | MEN1ALDH1A1LMNAHPGDKMT2A | |
| SCHEMBL29718982 | 0.59 | CYP1B1 (0.51) | CYP1A1CYP1A2CYP1B1MEN1ALDH1A1 | |
| SCHEMBL6333650 | 0.56 | PRKAB2 (0.35) | MEN1ALDH1A1LMNAHPGDKMT2A | |
| SCHEMBL6333518 | 0.56 | PRKAB2 (0.35) | MEN1ALDH1A1LMNAHPGDKMT2A | |
| SCHEMBL5940642 | 0.55 | CYP1A2 (0.54) | CYP1A1CYP1A2CYP1B1ALDH1A1 | |
| SCHEMBL15676021 | 0.54 | KMT2A (0.61) | CYP1A2MEN1ALDH1A1LMNAHPGD | |
| SCHEMBL21591570 | 0.54 | HPGD (0.47) | CYP1A1CYP1A2CYP1B1MEN1ALDH1A1 | |
| SCHEMBL1304537 | 0.54 | ATP1A1 (0.52) | MEN1ALDH1A1LMNAHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113185486-B | Antitumor agent 3-aryl-4H-chromen-4-one for the treatment of cancer | 肯塔基大学研究基金会 | 2024-05-10 | — | — | CN | disclosed |