Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP1A1 | P05023 | 2/20 | 0.52 |
| ▸ | ATP1B1 | P05026 | 2/20 | 0.52 |
| ▸ | ATP1A3 | P13637 | 2/20 | 0.52 |
| ▸ | ATP1B2 | P14415 | 2/20 | 0.52 |
| ▸ | ATP1A2 | P50993 | 2/20 | 0.52 |
| ▸ | ATP1B3 | P54709 | 2/20 | 0.52 |
| ▸ | FXYD2 | P54710 | 2/20 | 0.52 |
| ▸ | ATP1A4 | Q13733 | 2/20 | 0.52 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 7/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.47 |
| ▸ | MET | P08581 | 1/20 | 0.47 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.47 |
| ▸ | TERT | O14746 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12663610 | 0.81 | KDM4E (0.50) | FTOKDM4EALDH1A1MEN1HPGD | |
| SCHEMBL31632297 | 0.81 | KDM4E (0.47) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL27747720 | 0.77 | PTPN1 (0.49) | FTOKDM4EALDH1A1MEN1HPGD | |
| SCHEMBL30776625 | 0.77 | HPGD (0.53) | ALOX15KDM4EALDH1A1MEN1CYP3A4 | |
| SCHEMBL4369807 | 0.77 | ALDH1A1 (0.61) | ALOX15FTOTERTKDM4EALDH1A1 | |
| SCHEMBL30903616 | 0.73 | ALDH1A1 (0.52) | KDM4EALDH1A1MEN1MAPTHPGD | |
| SCHEMBL8467023 | 0.73 | SRD5A1 (0.52) | FTOKDM4EALDH1A1MEN1MAPT | |
| SCHEMBL28717873 | 0.71 | FTO (0.50) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL29516885 | 0.71 | FTO (0.50) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL11616702 | 0.70 | ALOX15 (0.52) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101279993-B | 3-aryl-8-hydroxychromone-7-O-alpha-D-arabinofuranoside compound, synthetic method and use thereof | SHANGHAI INST ORGANIC CHEM | 2011-10-12 | — | — | CN | claimed |
| CN-101279993-A | 3-aryl-8-hydroxychromone-7-O-alpha-D-arabinofuranoside compound, synthetic method and use thereof | SHANGHAI INST ORGANIC CHEM (CN) | 2008-10-08 | — | — | CN | claimed |
| US-8052963-B2 | [(4-oxo-4H-chromen-3-yl)hydroxymethyl]- or [(4-oxo-4H-chromen-3-yl)methyl]phosphonic acid derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-11-08 | — | — | US | disclosed |
| CN-101279993-B | 3-aryl-8-hydroxychromone-7-O-alpha-D-arabinofuranoside compound, synthetic method and use thereof | SHANGHAI INST ORGANIC CHEM | 2011-10-12 | — | — | CN | disclosed |
| EP-1979337-B1 | CHROMEN-4-ONE DERIVATIVES AS A SELF-TANNING SUBSTANCE | MERCK PATENT GMBH (DE) | 2011-05-25 | — | — | EP | disclosed |
| EP-1979337-B1 | CHROMEN-4-ONE DERIVATIVES AS A SELF-TANNING SUBSTANCE | MERCK PATENT GMBH (DE) | 2011-05-25 | — | — | EP | disclosed |
| US-20100004209-A1 | [(4-Oxo-4H-chromen-3-yl)hydroxymethyl]- or [(4-oxo-4H-chromen-3-yl)methyl]phosphonic acid derivatives | MERCK PATENT GESELLSCHAFT (DE) | 2010-01-07 | — | — | US | disclosed |
| US-20090220438-A1 | CHROMEN-4-ONE DERIVATIVES AS SELF-TANNING SUBSTANCE | MERCK PATENT GMBH (DE) | 2009-09-03 | — | — | US | disclosed |
| US-20090220438-A1 | CHROMEN-4-ONE DERIVATIVES AS SELF-TANNING SUBSTANCE | MERCK PATENT GMBH (DE) | 2009-09-03 | — | — | US | disclosed |
| US-20090220438-A1 | CHROMEN-4-ONE DERIVATIVES AS SELF-TANNING SUBSTANCE | MERCK PATENT GMBH (DE) | 2009-09-03 | — | — | US | disclosed |
| EP-1979337-A1 | CHROMEN-4-ONE DERIVATIVES AS A SELF-TANNING SUBSTANCE | Merck Patent GmbH (DE) | 2008-10-15 | — | — | EP | disclosed |
| CN-101279993-A | 3-aryl-8-hydroxychromone-7-O-alpha-D-arabinofuranoside compound, synthetic method and use thereof | SHANGHAI INST ORGANIC CHEM (CN) | 2008-10-08 | — | — | CN | disclosed |
| WO-2007087956-A1 | CHROMEN-4-ONE DERIVATIVES AS A SELF-TANNING SUBSTANCE | MERCK PATENT GMBH (DE) | 2007-08-09 | — | — | WO | disclosed |
| WO-2007087956-A1 | CHROMEN-4-ONE DERIVATIVES AS A SELF-TANNING SUBSTANCE | MERCK PATENT GMBH (DE) | 2007-08-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090220438-A1 | CHROMEN-4-ONE DERIVATIVES AS SELF-TANNING SUBSTANCE | C9, CYP8B1, TYR | ATP1A1 2588/4885ATP1B1 1991/4885ATP1A3 1930/4885 |
| US-20100004209-A1 | [(4-Oxo-4H-chromen-3-yl)hydroxymethyl]- or [(4-oxo-4H-chromen-3-yl)methyl]phosphonic acid derivatives | H1-4, H1-0, H1-5 | ATP1A1 1697/4885ATP1B1 1896/4885ATP1A3 2427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.