Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | PRKDC | P78527 | 1/20 | 0.44 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.42 |
| ▸ | TUBB | P07437 | 3/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.42 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.42 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30903833 | 0.84 | ALDH1A1 (0.45) | ERN1ALDH1A1CYP1A2CYP2C19LMNA | |
| SCHEMBL127848 | 0.82 | ERN1 (0.66) | ERN1ALDH1A1CYP1A2CYP2C19LMNA | |
| SCHEMBL18397169 | 0.82 | ALDH1A1 (0.54) | ERN1ALDH1A1CYP1A2CYP2C19LMNA | |
| SCHEMBL275629 | 0.78 | LMNA (0.61) | ERN1ALDH1A1CYP1A2CYP2C19LMNA | |
| SCHEMBL26936576 | 0.76 | ALDH1A1 (0.57) | ALDH1A1CYP1A2CYP2C19LMNACYP2C9 | |
| SCHEMBL38659181 | 0.75 | ALDH1A1 (0.71) | ERN1ALDH1A1CYP1A2CYP2C19LMNA | |
| SCHEMBL26936489 | 0.75 | TUBB1 (0.53) | ALDH1A1TUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL295318 | 0.74 | ALDH1A1 (0.61) | ERN1ALDH1A1CYP1A2CYP2C19LMNA | |
| SCHEMBL16475647 | 0.73 | ERN1 (0.68) | ERN1ALDH1A1CYP1A2CYP2C19LMNA | |
| SCHEMBL23663122 | 0.72 | TUBB1 (0.48) | ERN1ALDH1A1CYP1A2CYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114025847-B | Compounds and compositions as modulators of TLR signaling | 神经孔疗法股份有限公司 | 2024-05-24 | — | — | CN | disclosed |