Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 4/20 | 0.33 |
| ▸ | PLA2G7 | Q13093 | 4/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.33 |
| ▸ | BRD1 | O95696 | 2/20 | 0.32 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.32 |
| ▸ | BRPF3 | Q9ULD4 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27238839 | 1.00 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL31575236 | 0.81 | KDM4E (0.35) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL22434878 | 0.75 | TRPV4 (0.37) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL31589251 | 0.75 | F2RL1 (0.39) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL27238858 | 0.73 | AR (0.34) | AR | |
| SCHEMBL28161697 | 0.72 | BRPF1 (0.34) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL31589484 | 0.69 | F2RL1 (0.42) | MEN1KMT2AKDM4EKDM1ATRPV4 | |
| SCHEMBL15797658 | 0.68 | KDM4E (0.47) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL31589478 | 0.68 | AR (0.40) | ALDH1A1KDM4EARPGRTRPV4 | |
| SCHEMBL30903892 | 0.67 | KDM4E (0.34) | ALDH1A1MEN1KMT2AKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024102784-A1 | SUBSTITUTED QUINOLINONE-8-CARBONITRILE DERIVATIVES HAVING ANDROGEN DEGRADATION ACTIVITY AND USES THEREOF | ACCUTAR BIOTECHNOLOGY, INC. (US) | 2024-05-16 | — | — | WO | disclosed |