Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | ACP1 | P24666 | 3/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | ASPH | Q12797 | 1/20 | 0.39 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.39 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30904786 | 1.00 | FAAH (0.44) | FAAHCES1ACP1GABRG2GABRB3 | |
| SCHEMBL29206815 | 0.86 | ACP1 (0.46) | FAAHCES1ACP1KDM4EALDH1A1 | |
| SCHEMBL30904777 | 0.86 | ACP1 (0.46) | FAAHCES1ACP1KDM4EALDH1A1 | |
| SCHEMBL29206792 | 0.80 | ACP1 (0.41) | FAAHCES1ACP1KDM4EALDH1A1 | |
| SCHEMBL30904773 | 0.80 | ACP1 (0.41) | FAAHCES1ACP1KDM4EALDH1A1 | |
| SCHEMBL29206806 | 0.71 | FAAH (0.42) | FAAHCES1ACP1GABRG2GABRB3 | |
| SCHEMBL30904787 | 0.71 | FAAH (0.42) | FAAHCES1ACP1GABRG2GABRB3 | |
| SCHEMBL29206795 | 0.71 | KMT2A (0.55) | FAAHCES1KDM4EALDH1A1HPGD | |
| SCHEMBL29206798 | 0.71 | PKM (0.47) | KDM4EALDH1A1HPGDSMN1; SMN2RPS6KB1 | |
| SCHEMBL30904776 | 0.69 | FAAH (0.42) | FAAHCES1ACP1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118005615-A | Pyridazine compound and preparation method, pharmaceutical composition and application thereof | 中国药科大学 | 2024-05-10 | — | — | CN | disclosed |