Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.47 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.41 |
| ▸ | MAP2K6 | P52564 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | MAP3K19 | Q56UN5 | 1/20 | 0.41 |
| ▸ | NEK10 | Q6ZWH5 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27401714 | 1.00 | PKMYT1 (0.47) | PKMYT1CDK9DYRK1AALOX15LCK | |
| SCHEMBL27401713 | 0.87 | KMT2A (0.46) | PKMYT1TP53HSD17B10ALDH1A1KDM4E | |
| SCHEMBL30905584 | 0.87 | KMT2A (0.46) | PKMYT1TP53HSD17B10ALDH1A1KDM4E | |
| SCHEMBL30905495 | 0.84 | PKMYT1 (0.44) | PKMYT1LCKMAP2K3MAP2K6BTK | |
| SCHEMBL30905494 | 0.84 | PKMYT1 (0.44) | PKMYT1LCKMAP2K3MAP2K6BTK | |
| SCHEMBL27397758 | 0.84 | PKMYT1 (0.44) | PKMYT1LCKMAP2K3MAP2K6BTK | |
| SCHEMBL27401362 | 0.83 | PKMYT1 (0.44) | PKMYT1IKBKBALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL26606785 | 0.77 | IKBKB (0.53) | CDK9DYRK1AALOX15IKBKBTP53 | |
| SCHEMBL27401560 | 0.76 | GRM2 (0.58) | ALOX15ALDH1A1KDM4E | |
| SCHEMBL30971039 | 0.75 | PKMYT1 (0.38) | PKMYT1ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4622967-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | Exelixis, Inc. (US) | 2025-10-01 | — | — | EP | disclosed |
| WO-2024112853-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | EXELIXIS, INC. (US) | 2024-05-30 | — | — | WO | disclosed |