Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30905510 | 0.88 | PKMYT1 (0.40) | PKMYT1PRMT5LMNAMAPTRAB9A | |
| SCHEMBL27401343 | 0.88 | PKMYT1 (0.40) | PKMYT1PRMT5LMNAMAPTRAB9A | |
| SCHEMBL27399923 | 0.87 | BRD4 (0.35) | PKMYT1PRMT5LMNAMAPTRAB9A | |
| SCHEMBL27397408 | 0.86 | IKBKB (0.41) | PKMYT1LMNAMAPTRAB9AKDM4E | |
| SCHEMBL30905539 | 0.86 | IKBKB (0.41) | PKMYT1LMNAMAPTRAB9AKDM4E | |
| SCHEMBL30905573 | 0.85 | PKMYT1 (0.42) | PKMYT1PRMT5LMNAKDM4EPARP1 | |
| SCHEMBL27397362 | 0.85 | PKMYT1 (0.42) | PKMYT1PRMT5LMNAKDM4EPARP1 | |
| SCHEMBL30905482 | 0.83 | PKMYT1 (0.47) | PKMYT1MAPTKDM4ENPC1POLB | |
| SCHEMBL27401714 | 0.83 | PKMYT1 (0.47) | PKMYT1MAPTKDM4ENPC1POLB | |
| SCHEMBL27398649 | 0.82 | MKNK1 (0.35) | PKMYT1PRMT5LMNAMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024112853-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | EXELIXIS, INC. (US) | 2024-05-30 | — | — | WO | disclosed |